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Ⅰ型前膠原羧基端原肽(PICP)多克隆抗體

Polyclonal Antibody to Procollagen I C-Terminal Propeptide (PICP)

P1CP; C-Propeptide Of Type I Procollagen; Procollagen I Carboxy Terminal Propeptide

  • Ⅰ型前膠原羧基端原肽(PICP)多克隆抗體 產(chǎn)品包裝(模擬)
  • Ⅰ型前膠原羧基端原肽(PICP)多克隆抗體 產(chǎn)品包裝(模擬)
  • Certificate 通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對(duì)PICP的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別PICP。

用法

Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲(chǔ)存

經(jīng)常使用則4°C保存。-20°C保存不超過(guò)兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。

贈(zèng)品

相關(guān)產(chǎn)品

編號(hào) 適用物種：Homo sapiens (Human，人) 應(yīng)用(僅供研究使用，不用于臨床診斷！)
RPA570Hu01 Ⅰ型前膠原羧基端原肽(PICP)重組蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
EPA570Hu61 Ⅰ型前膠原羧基端原肽(PICP)真核蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
APA570Hu61 Ⅰ型前膠原羧基端原肽(PICP)活性蛋白 Cell?culture;?Activity?Assays.
CPA570Hu22 Ⅰ型前膠原羧基端原肽(PICP)卵白蛋白偶聯(lián)物 Immunogen; SDS-PAGE; WB.
CPA570Hu21 Ⅰ型前膠原羧基端原肽(PICP)卵白蛋白偶聯(lián)物 Immunogen; SDS-PAGE; WB.
PAA570Hu01 Ⅰ型前膠原羧基端原肽(PICP)多克隆抗體 WB; IHC; ICC; IP.
PAA570Hu08 Ⅰ型前膠原羧基端原肽(PICP)多克隆抗體 WB; IHC; ICC; IP.
SEA570Hu Ⅰ型前膠原羧基端原肽(PICP)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA570Hu Ⅰ型前膠原羧基端原肽(PICP)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
LMA570Hu Ⅰ型前膠原羧基端原肽(PICP)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) FLIA Kit for Antigen Detection.

參考文獻(xiàn)

雜志 參考文獻(xiàn)
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American Heart Journal Serum markers of deranged myocardial collagen turnover: their relation to malignant ventricular arrhythmias in cardioverter-defibrillator recipients with heart failure. [PubMed: 23067911]
Journal of Hypertension Circulating biomarkers of collagen metabolism in arterial hypertension: relevance of target organ damage [Pubmed: 23615327]
Pancreatology Cdkn1a is a key mediator of rat pancreatic stellate cell senescence [Pubmed: 23719597]
The American Journal of Cardiology Relation of burden of myocardial fibrosis to malignant ventricular arrhythmias and outcomes in Fabry disease [Pubmed:25073565]
PLoS One. An NMR Metabolomic Study on the Effect of Alendronate in Ovariectomized Mice [Pubmed:25184758]
Journal of Bone and Mineral Research The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5 [Pubmed:25640331]
Bone The active role of osteoporosis in the interaction between osteoblasts and bone metastases [PubMed: 26057367]
J Nutr Biochem Consumption of vitamin D2 [PubMed: 25792284]
Bibliothekssystem Universit?t Hamburg Bilaterale Kommunikation zwischen Osteoblasten und Osteoklasten [volltexte:2016]
Inflammation Research Fibrosis of extracellular matrix is related to the duration of the disease but is unrelated to the dynamics of collagen metabolism in dilated cardiomyopathy [pubmed:27516211]
Heart & Vessels Left ventricular reverse remodeling is not related to biopsy-detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR [pubmed:28004175]
Scandinavian?Journal?of?Rheumatology The?association?between?insulin-like?growth?factor?1?(IGF-1),?IGF-binding?proteins?(IGFBPs), and the?carboxyterminal?propeptide?of?type?I?procollagen?(PICP) in pre- and postmenopausal women with rheumatoid arthritis. [pubmed:27775453]
Allergy?and?Asthma?Proceedings Effect?of?montelukast?on?markers?of?airway remodeling?in?children?withasthma. [pubmed:27657514]
Scandinavian Journal of Rheumatology The association between insulin-like growth factor 1 (IGF-1), IGF-binding proteins (IGFBPs), and the carboxyterminal propeptide of type I procollagen (PICP) in pre- and postmenopausal women with rheumatoid arthritis [loi:irhe20]
Conditional Mouse Models Support the Role of SLC39A14 (ZIP14) in Hyperostosis Cranialis Interna and in Bone Homeostasis [ISBN: 978-94-6299-582-6]
MOLECULAR MEDICINE REPORTS Endothelial?to?mesenchymal transition in human idiopathic dilated cardiomyopathy [pubmed:29115553]
Pediatrics and Neonatology Age-related changes in biochemical bone profile in thalassemic children [pubmed:28967496]
Heart and Vessels Left ventricular reverse remodeling is not related to biopsy?detected extracellular matrix fibrosis and serum markers of fibrosis in dilated cardiomyopathy, regardless of the definition used for LVRR [10.1007/s00380-016-0930-y]
Journal of Bone and Mineral Research The Lrp4 R1170Q homozygous knock‐in mouse recapitulates the bone phenotype of sclerosteosis in humans [pubmed:28477420]
Cytokine 12-month patterns of serum markers of collagen synthesis, transforming growth factor and connective tissue growth factor are similar in new-onset and chronic dilated cardiomyopathy in patients both with and without cardiac fibrosis. [pubmed:28460256]
Advanced Healthcare Materials Prognostic value of fibrosis-related markers in dilated cardiomyopathy: A link between osteopontin and cardiovascular events. [pubmed:29120858]
Journal of?Bone?and?Mineral?Metabolism Mutations That Alter the Carboxy‐Terminal‐Propeptide Cleavage Site of the Chains of Type I Procollagen Are Associated With a Unique Osteogenesis Imperfecta?… [Pubmed:29669177]
Cardiovascular Journal of Africa Assessment of myocardial fibrosis by late gadolinium enhancement imaging and biomarkers of collagen metabolism in chronic rheumatic mitral regurgitation. [Pubmed:29443354]
Journal?of?Cellular?Physiology DNA methylation regulates α‐smooth muscle actin expression during cardiac fibroblast differentiation [Pubmed: 30362530]
International Journal of Chronic Obstructive Pulmonary Disease Altered serum levels of type I collagen turnover indicators accompanied by IL-6 and IL-8 release in stable COPD [Pubmed: 30655663]
Scientific Reports Low fibrosis biomarker levels predict cardiac resynchronization therapy response [Pubmed: 30988339]
Bone Agonist-induced activation of the S1P receptor 2 constitutes a novel osteoanabolic therapy for the treatment of osteoporosis in mice [Pubmed: 31028959]
PLoS One Deficiency of sphingosine-1-phosphate receptor 3 does not affect the skeletal phenotype of mice lacking sphingosine-1-phosphate lyase [Pubmed: 31314788]
Bone Mice lacking plastin-3 display a specific defect of cortical bone acquisition [Pubmed: 31678489]
Journal of Diabetes Research Type 2 Diabetes Mellitus and Chronic Heart Failure with Midrange and Preserved Ejection Fraction: A Focus on Serum Biomarkers of Fibrosis [Pubmed: 33224989]
JOURNAL OF BONE AND MINERAL RESEARCH Piezo1 Inactivation in Chondrocytes Impairs Trabecular Bone Formation [Pubmed: 33180356]
Microbiome changes in patients with chronic heart failure with preserved ejection fraction correlate with fibrosis markers: Description of a Russian cohort []
Ассоциации толщины эпикардиального жира и циркулирующих маркеров фиброза миокарда у пациентов с инфарктом миокарда []
Russian Journal of Cardiology Early diagnosis of myocardial fibrosis in patients with epicardial obesity []
J Diabetes Res Association between Markers of Fibrosis and Heart Failure Incidence in Patients with Type 2 Diabetes Mellitus [34778465]
Clinical, Cosmetic and Investigational Dermatology Extra Cellular Matrix Deposition and Assembly in Dermis Spheroids [34321901]
Scandinavian Cardiovascular Journal Dual integrin αvβ3 and αvβ5 blockade attenuates cardiac dysfunction by reducing fibrosis in a rat model of doxorubicin-induced cardiomyopathy [34296634]
Eur J Appl Physiol Effects of 8-week increment aerobic exercise program on bone metabolism and body composition in young non-athletes [Pubmed:35141785]
J. Clin. Med Simple Predictors for Cardiac Fibrosis in Patients with Type 2 Diabetes Mellitus: The Role of Circulating Biomarkers and Pulse Wave Velocity [Pubmed:35628969]
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