膜聯(lián)蛋白A1(ANXA1)重組蛋白
Recombinant Annexin A1 (ANXA1)
ANX-A1; ANX1; LPC1; Lipocortin I; Chromobindin-9; Calpactin II; Phospholipase A2 inhibitory protein
- 編號(hào)RPE787Mu01
- 物種Mus musculus (Mouse，小鼠) 相同的名稱，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位細(xì)胞膜, 細(xì)胞核, 分泌, 細(xì)胞質(zhì)
- 預(yù)測(cè)分子量44.9kDa
- 實(shí)際分子量44kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
- 片段與標(biāo)簽Glu6~Asn346 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 90%
- 等電點(diǎn)6.2
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載 英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure . Gene Sequencing (extract)
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SDS-PAGE圖
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通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
贈(zèng)品
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相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Mus musculus (Mouse，小鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPE787Mu01 | 膜聯(lián)蛋白A1(ANXA1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPE787Mu02 | 膜聯(lián)蛋白A1(ANXA1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APE787Mu01 | 膜聯(lián)蛋白A1(ANXA1)活性蛋白 | Cell?culture;?Activity?Assays. |
| PAE787Mu01 | 膜聯(lián)蛋白A1(ANXA1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAE787Mu02 | 膜聯(lián)蛋白A1(ANXA1)多克隆抗體 | WB; IHC; ICC; IP. |
| LAE787Mu71 | 膜聯(lián)蛋白A1(ANXA1)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| SEE787Mu | 膜聯(lián)蛋白A1(ANXA1)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LME787Mu | 膜聯(lián)蛋白A1(ANXA1)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| KSE787Mu01 | 膜聯(lián)蛋白A1(ANXA1)檢測(cè)試劑盒DIY材料(酶聯(lián)免疫吸附試驗(yàn)法) | 自己動(dòng)手制作ELISA試劑盒的主要材料 |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Plos one | Dysregulation of Anti-Inflammatory Annexin A1 Expression in Progressive Crohns Disease [PubMed: PMC3794972] |
| African Journals Online | Modulatory Effect of Phytoestrogens and Curcumin on Induction of Annexin 1 in Human Peripheral Blood Mononuclear Cells and their Inhibitory Effect on Secretory Phospholipase A2 [Ajol: Source] |
| Antimicrobial Agents and Chemotherapy | Host Biomarkers of Invasive Pulmonary Aspergillosis to Monitor Therapeutic Response [Asm: Source] |
| J Proteomics | Characterization of secretomes from a human blood brain barrier endothelial cells in-vitro model after ischemia by stable isotope labeling with aminoacids in cell culture (SILAC) [PubMed: 26718731] |
| Diabetes | Annexin A1 Is a Key Modulator of Mesenchymal Stromal Cell–Mediated Improvements in Islet Function [PubMed: 26470781] |
| PLoS One | Annexin A1 Is Increased in the Plasma of Preeclamptic Women [PubMed: 26398190] |
| 中國(guó)現(xiàn)代醫(yī)學(xué)雜志 China Journal of Modern Medicine | 膜聯(lián)蛋白A1 和CA19-9 在膽管癌中的表達(dá)及其臨床意義 [article:8686] |
| arteriosclerosis thrombosis and vascular biology | Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report. [pubmed:28062503] |
| Clinical Science | Mesenchymal stromal cells improve human islet function through released products and extracellular matrix. [pubmed:29101297] |
| Biomedicine & Pharmacotherapy | Proresolving protein Annexin A1: The role in type 2 diabetes mellitus and obesity [Pubmed:29677533] |
| ?International Journal of?Chronic?Obstructive Pulmonary Disease | Annexin A1 is elevated in patients with COPD and affects lung fibroblast function [Pubmed:29440885] |
| Medical?Mycology | Applying host disease status biomarkers to therapeutic response monitoring in invasive aspergillosis patients [Pubmed:29370415] |
| DEVELOPMENTAL NEUROPSYCHOLOGY | EFFECTS OF MULTICOMPONENT EXERCISE ON PROGRESSION OF BRAIN ATROPHY AND COGNITION IN AMNESTIC MILD COGNITIVE IMPAIRMENT?… [pdf:3395] |
| Multiple sclerosis and related disorders | Resolution of inflammation in neuromyelitis optica spectrum disorders [Pubmed: 30300851] |
| Acta Pharmaceutica | Effects of annexin A1 on apoptosis and cell cycle arrest in human leukemic cell lines [] |
| npj Science of Food | Annexin A1 accounts for an anti-inflammatory binding target of sesamin metabolites [Pubmed: 32133417] |
| FASEB JOURNAL | ANXA1 directs Schwann cells proliferation and migration to accelerate nerve regeneration through the FPR2/AMPK pathway [Pubmed: 32908567] |
| Rev Soc Bras Med Trop | Expression of annexin-A1 in blood and tissue leukocytes of leprosy patients [33263684] |
| science advances | Annexin-A1 SUMOylation regulates microglial polarization after cerebral ischemia by modulating IKK|á stability via selective autophagy [33523920] |
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