酸性神經(jīng)鞘磷脂酶(ASM)多克隆抗體
Polyclonal Antibody to Acid Sphingomyelinase (ASM)
SMPD1; NPD; SMase; aSMase; Sphingomyelin Phosphodiesterase 1,Acid Lysosomal; Simply Sphingomyelinase
- 編號PAB360Hu01
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標(biāo)記物無標(biāo)記物
- 免疫原 RPB360Hu01-酸性神經(jīng)鞘磷脂酶(ASM)重組蛋白
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度0.5mg/mL
- 且適物種Mus musculus (Mouse，小鼠), Sus scrofa; Porcine (Pig，豬)
- 應(yīng)用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 598 ¥ 1394 ¥ 1992 ¥ 4980 ¥ 19920
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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DAB staining on IHC-P; Samples: Human Cerebrum Tissue; Primary Ab: 20μg/ml Rabbit Anti-Human ASM Antibody Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
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Figure. Western Blot; Sample: Recombinant ASM, Human.
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Figure. Western Blot; Sample: Mouse Brain Tissue.
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
特異性
該抗體是針對ASM的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別ASM。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| EPB360Hu61 | 酸性神經(jīng)鞘磷脂酶(ASM)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB360Hu01 | 酸性神經(jīng)鞘磷脂酶(ASM)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB360Hu61 | 酸性神經(jīng)鞘磷脂酶(ASM)活性蛋白 | Cell?culture;?Activity?Assays. |
| PAB360Hu01 | 酸性神經(jīng)鞘磷脂酶(ASM)多克隆抗體 | WB; IHC; ICC; IP. |
| MAB360Hu22 | 酸性神經(jīng)鞘磷脂酶(ASM)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB360Hu | 酸性神經(jīng)鞘磷脂酶(ASM)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| MEB360Hu | 酸性神經(jīng)鞘磷脂酶(ASM)檢測試劑盒(酶聯(lián)免疫吸附試驗法,小樣本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB360Hu | 酸性神經(jīng)鞘磷脂酶(ASM)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Blood.? | Acid sphingomyelinase is activated in sickle cell erythrocytes and contributes to inflammatory microparticle generation in SCD [Pubmed:25075126] |
| Journal of Clinical Lipidology | Increase in acid sphingomyelinase level in human retinal endothelial cells and CD34+ circulating angiogenic cells isolated from diabetic individuals is associated with dysfunctional retinal vasculature and vascular repair process in diabetes [10.1016/j.jacl.2017.03.007] |
| Diabetes & metabolism | Fenofibrate decreases plasma ceramide in type 2 diabetes patients: A novel marker of CVD? [pubmed:28499696] |
| INFLAMMATION | Acid Sphingomyelinase and Acid |?-Glucosidase 1 Exert Opposite Effects on Interleukin-1|?-Induced Interleukin 6 Production in Rheumatoid Arthritis Fibroblast-Like Synoviocytes [33665756] |
| Indian J Ophthalmol | Evaluation of sphingolipid metabolism on diabetic retinopathy [34708809] |
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