腦源性神經(jīng)營(yíng)養(yǎng)因子(BDNF)多克隆抗體
Polyclonal Antibody to Brain Derived Neurotrophic Factor (BDNF)
Neurotrophin; Abrineurin
- 編號(hào)PAA011Ca01
- 物種Canis familiaris; Canine (Dog,犬) 相同的名稱,不同的物種。
- 來(lái)源多抗制備
- 宿主兔
- 效價(jià)-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標(biāo)記物無(wú)標(biāo)記物
- 免疫原 RPA011Ca01-腦源性神經(jīng)營(yíng)養(yǎng)因子(BDNF)重組蛋白
- 緩沖液成份磷酸鹽緩沖液(pH7.4,含有0.02% NaN3和50%甘油)
- 性狀液體
- 濃度500μg/mL
- 且適物種Mus musculus (Mouse,小鼠)
- 應(yīng)用WB; IHC; ICC; IP.
如果抗體需用于流式細(xì)胞術(shù),請(qǐng)參見(jiàn)流式抗體。 - 下載 英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價(jià)格 ¥ 648 ¥ 1512 ¥ 2160 ¥ 5400 ¥ 21600
- 欲了解實(shí)際交易價(jià)格和更多情況,請(qǐng)與當(dāng)?shù)亟?jīng)銷商聯(lián)系!
特異性
該抗體是針對(duì)BDNF的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別BDNF。
用法
Western blotting: 0.5-2μg/mL
Immunohistochemistry: 5-20μg/mL
Immunocytochemistry: 5-20μg/mL
Optimal working dilutions must be determined by end user.
儲(chǔ)存
經(jīng)常使用則4°C保存。-20°C保存不超過(guò)兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定,具體方法如下:在37°C孵育48小時(shí),沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲(chǔ),損失率低于5%。
贈(zèng)品
增值服務(wù)
抗體標(biāo)記定制服務(wù)
Protein-A/G純化柱
細(xì)胞和組織染色液
抗體陽(yáng)性對(duì)照品
組織/切片定制服務(wù)
磷酸化抗體定制服務(wù)
免疫印跡(WB)實(shí)驗(yàn)服務(wù)
免疫組織化學(xué)(IHC)實(shí)驗(yàn)服務(wù)
免疫細(xì)胞化學(xué)(ICC)實(shí)驗(yàn)服務(wù)
流式細(xì)胞術(shù)(FCM)實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
免疫熒光(IF)實(shí)驗(yàn)服務(wù)
緩沖液
DAB顯色試劑盒
SABC試劑盒
長(zhǎng)臂生物素標(biāo)記試劑盒
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
相關(guān)產(chǎn)品
編號(hào) | 適用物種:Canis familiaris; Canine (Dog,犬) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) |
RPA011Ca01 | 腦源性神經(jīng)營(yíng)養(yǎng)因子(BDNF)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAA011Ca01 | 腦源性神經(jīng)營(yíng)養(yǎng)因子(BDNF)多克隆抗體 | WB; IHC; ICC; IP. |
MAA011Ca21 | 腦源性神經(jīng)營(yíng)養(yǎng)因子(BDNF)單克隆抗體 | WB; IHC; ICC; IP. |
SEA011Ca | 腦源性神經(jīng)營(yíng)養(yǎng)因子(BDNF)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMA011Ca | 腦源性神經(jīng)營(yíng)養(yǎng)因子(BDNF)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
雜志 | 參考文獻(xiàn) |
Toxicological Sciences | Interaction of PFOS and BDE-47 Co-exposure on Thyroid Hormone Levels and TH-Related Gene and Protein Expression in Developing Rat Brains [PubMed: 21436126] |
Journal of the Neurological Sciences | Neuroprotective effects of adipose-derived stem cells against ischemic neuronal damage in the rabbit spinal cord [ScienceDirect: S0022510X12001219] |
International Conference on Bioscience | Effect of Benthosemapterotum Peptide on Aging in Mice with Oxidative Damage [Psrcentre: 212059] |
Neuroscience Letters | Chronic stress impairs learning and hippocampal cell proliferation in senescence-accelerated prone mice [ScienceDirect: S0304394010015788] |
BioMed Research International | Neuroprotective effects of adipose-derived stem cells are maintained for 3 weeks against ischemic damage in the rabbit spinal cord. [NCBI: PMC3925622] |
Behavioural Brain Research | The effects of Ginkgo biloba extract on cognitive functions in aged female rats: The role of oxidative stress and brain-derived neurotrophic factor [Pubmed:25446810] |
Neurochemical Research | Heme?Oxygenase-1?Protects?Neurons?from?Ischemic?Damage?by?UpreCavia (Guinea pig )lating?Expression?of?Cu,Zn-SuperoxideDismutase,?Catalase, and?Brain-Derived?Neurotrophic?Factor?in the?Rabbit?Spinal?Cord. [Pubmed:26559686] |
Exp Ther Med. | Effects of docosahexaenoic acid on learning and memory impairment induced by repeated propofol anesthesia in young rats [pmc:PMC4812310] |
Genet Mol Res | Changes in growth factor levels in the cerebrospinal fluid of autism patients after transplantation of human umbilical cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells [Pubmed:27323064] |
The International Journal af Applied Research in Veterinary Medicine | Effect of Sample Time in Clot Tube, Temperature, and Hemolysis Status on Canine Serum Brain-Derived Neurotrophic Factor (BDNF) Concentrations: Preliminary study [articles:Vol14Iss3] |
J Chem Neuroanat. | Both secreted and the cellular levels of BDNF attenuated due to tau hyperphosphorylation in primary cultures of cortical neurons. [pubmed:27914953] |
Int Immunopharmacol. | PPARr activation ameliorates postoperative cognitive decline probably through suppressing hippocampal neuroinflammation in aged mice. [pubmed:27940378] |
The Journal of Maternal-Fetal & Neonatal Medicine | Differential expression of cord blood neurotrophins in gestational diabetes: the impact of fetal growth abnormalities [pubmed:28081639] |
IOS Press Content Library | An Intranasal Formulation of Erythropoietin (Neuro-EPO) Prevents Memory Deficits and Amyloid Toxicity in the APPSwe Transgenic Mouse Model of Alzheimer's … [articles:journal-of-alzheimers-disease] |
Bipolar Disorders | Long‐term lithium treatment increases intracellular and extracellular brain‐derived neurotrophic factor (BDNF) in cortical and hippocampal neurons at subtherapeutic … [bdi.12449] |
Elsevier | Associations of blood parameters with age, feed efficiency and sampling routine in young beef bulls [science:article] |
journal of?allergy?and?clinical?immunology | Water-soluble chitosan inhibits nerve growth factor and attenuates allergic inflammation in mite allergen–induced allergic rhinitis [pubmed:28412394] |
American Journal of Translational Research | A new comorbidity model and the common pathological mechanisms of migraine and epilepsy [pubmed:28559979] |
European Journal of Pharmacology | Alpha-asarone attenuates depression-like behavior in nicotine-withdrawn mice: Evidence for the modulation of hippocampal pCREB levels during nicotine-withdrawal. [pubmed:29042206] |
Brain,?Behavior, and?Immunity | An enriched environment restores hepatitis B vaccination-mediated impairments in synaptic function through IFN-γ/Arginase1 signaling [Pubmed:29627530] |
Stem?Cell?Research?&?Therapy | Autophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model [Pubmed:29335016] |
Pharmacological?Research? | N-3 PUFA diet enrichment prevents amyloid beta-induced depressive-like phenotype [Pubmed:29203442] |
Experimental Neurology | Preterm umbilical cord blood derived mesenchymal stem/stromal cells protect preterm white matter brain development against hypoxia-ischemia [Pubmed:30012511] |
Nutrients | Early Life Vitamin C Deficiency Does Not Alter Morphology of Hippocampal CA1 Pyramidal Neurons or Markers of Synaptic Plasticity in a Guinea Pig Model. [Pubmed:29890692] |
Neurotoxicity Research | Delta-9-Tetrahydrocannabinol (?-THC) Induce Neurogenesis and Improve Cognitive Performances of Male Sprague Dawley Rats [Pubmed:28933048] |
Neurotoxicology | Amelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats [Pubmed:29522778] |
Neuroscience Letters | Long term Westernized diet leads to region-specific changes in brain signaling mechanisms [Pubmed:29655945] |
Applied?Physiology Nutrition and Metabolism | Changes in exercise capacity and serum BDNF following long-term sprint interval training in well-trained cyclists [Pubmed: 30286300] |
Heliyon | Establishment and evaluation of a novel mouse model of peri/postmenopausal depression [Doi: 10.1016/j.heliyon.2019.e01195] |
BioMed Research International | Administration of Repetitive Transcranial Magnetic Stimulation Attenuates Aβ1-42-Induced Alzheimer's Disease in Mice by Activating β-Catenin Signaling [] |
International Journal of Immunopathology and Pharmacology | Effect of voluntary running on expression of myokines in brains of rats with depression [Pubmed: 30834799] |
American Journal of Emergency?Medicine | Clinical usefulness of brain-derived neurotrophic factor and visinin-like protein-1 in early diagnostic tests for acute stroke [Pubmed: 30826210] |
Neurochemistry International | Monoaminergic system is implicated in the antidepressant-like effect of hyperoside and protocatechuic acid isolated from Impatiens glandulifera Royle in mice [Pubmed: 31077758] |
REVISTA DA ASSOCIACAO MEDICA BRASILEIRA | Physical Exercise Increased Brain-Derived Neurotrophic Factor in Elderly Population with Depression [Pubmed: 30994834] |
Journal of Alzheimer's Disease | Regular Exercise Enhances Cognitive Function and Intracephalic GLUT Expression in Alzheimer's Disease Model Mice [Pubmed: 31561359] |
Biological Trace Element Research | Cognitive Decline of Rats with Chronic Fluorosis Is Associated with Alterations in Hippocampal Calpain Signaling [Pubmed: 31797207] |
Psychopharmacology | Chronic harmine treatment has a delayed effect on mobility in control and socially defeated rats [Pubmed: 32088835] |
Experimental and Therapeutic Medicine | Involvement of neurotrophic signaling in doxorubicin?induced cardiotoxicity [Pubmed: 32010279] |
Journal of Critical Care | Association of neuronal repair biomarkers with delirium among survivors of critical illness [Pubmed: 31896448] |
Journal of Clinical Neuroscience | CSF levels of a set of neurotrophic factors (brain-derived neurotrophic factor, nerve growth factor) and neuropeptides (neuropeptide Y, galanin) in epileptic children [Pubmed: 32327377] |
MOLECULAR NUTRITION & FOOD RESEARCH | Hyperlipidemia Down‐Regulate Brain Antioxidant Defense Enzymes and Neurotrophins in Rats: Assessment of the Modulatory Potential of EPA+ DHA and?… [Pubmed: 32918393] |
Neuropharmacology | Impaired LTD-like motor cortical plasticity in female patients with major depression disorder [Pubmed: 32791084] |
COLLOIDS AND SURFACES B-BIOINTERFACES | Effects of gold nanoparticles administration through behavioral and oxidative parameters in animal model of parkinson's disease [Pubmed: 32777662] |
Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice [Pubmed: 32522471] |
Journal of Veterinary Behavior | Comparison of serum brain-derived neurotrophic factor (BDNF) in dogs with and without separation anxiety [] |
Food & Function | Nicotinamide riboside alleviates alcohol-induced depression-like behaviours in C57BL/6J mice by altering the intestinal microbiota associated with microglial?… [] |
Short-but no long-term effect of social stress in rodent depressive-like behavior is not affected by chronic treatment with Harmine [] | |
bioinformatics and biomedical engineering | Blood Plasma Trophic Growth Factors Predict the Outcome in Patients with Acute Ischemic Stroke [] |
Overektomize di?i s??anlarda beyin oksidatif stres, bdnf ve inflamatuar cevap düzeyleri ile n?rodavran??sal de?i?iklikler üzerine anjiyotensin II ?nhibisyonunun etkisi [] | |
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY | Increased serum brain-derived neurotrophic factor and adrenocorticotropic hormone levels are associated with obsessive compulsive disorder in medication?free??- [33389158] |
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | Sea urchin gangliosides exhibit neuritogenic effects in neuronal PC12 cells via TrkA- and TrkB-related pathways [33589896] |
Neuropsychiatr Dis Treat | Repetitive Transcranial Magnetic Stimulation Improves Mild Cognitive Impairment Associated with Alzheimer's Disease in Mice by Modulating the miR-567?… [34239303] |
Einstein (Sao Paulo) | Tropomyosin receptor kinase B-mediated signaling in integration of neuropathic pain and obesity in diabetic polyneuropathy [34586159] |
Metab Brain Dis | Moderate-intensity continuous training and high-intensity interval training improve cognition, and BDNF levels of middle-aged overweight men [34762211] |
Transl Psychiatry | Lithium augmentation of ketamine increases insulin signaling and antidepressant-like active stress coping in a rodent model of treatment-resistant depression [34824208] |
Iranian Journal of Basic Medical Sciences | Adrenomedullin increases cAMP accumulation and BDNF expression in rat DRG and spinal motor neurons [34712429] |
J Sex Med | Endogenous Deficiency of Brain-Derived Neurotrophic Factor Induces the Downregulation of Tryptophan Hydroxylase-2 Expression in Raphe Nuclei of Rapid?… [34384732] |
Cell Biochem Funct | CNTs‐CaP/chitosan‐coated AZ91D magnesium alloy extract promoted rat dorsal root ganglia neuron growth via activating ERK signalling pathway [34296452] |
J Endocrinol Invest | Serum alpha-melanocyte-stimulating hormone (a-MSH), brain-derived neurotrophic factor (BDNF), and agouti-related protein (AGRP) levels in children with Prader?… [Pubmed:35098494] |
Clinical Rheumatology | Gender influence on clinical manifestations, depressive symptoms and brain-derived neurotrophic factor (BDNF) serum levels in patients affected by?… [Pubmed:35344113] |
Sci Rep | Associations between serum levels of brain-derived neurotrophic factor, corticotropin releasing hormone and mental distress in vitiligo patients [Pubmed:35508633] |
Pharmaceutics | Co-Delivery of Docosahexaenoic Acid and Brain-Derived Neurotropic Factor from Electrospun Aligned Core–Shell Fibrous Membranes in Treatment of Spinal Cord?… [Pubmed:35214053] |
Molecular Biology Reports | Umbilical cord-derived mesenchymal stem cell conditioned medium reverses neuronal oxidative injury by inhibition of TRPM2 activation and the JNK signaling?… [Pubmed:35585377] |
Journal of Complementary Medicine Research | Effect of herbal formulation Sharbat Ahmad Shahi on serum BDNF level in mild to moderate cases of depressive disorder [] |
AFRICAN JOURNAL OF BIOCHEMISTRY RESEARCH | Medicinal effects of Saffron on obese animals by reducing Castellis risk index to protect from cardio-pathology and psychological distress [] |