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轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法)

CLIA Kit for Transforming Growth Factor Beta 1 (TGFb1)

TGF-B1; CED; DPD1; LAP; Camurati-Engelmann Disease; Latency-associated peptide

  • 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) 產(chǎn)品包裝(模擬)
  • 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) 產(chǎn)品包裝(模擬)
  • 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) 實(shí)驗(yàn)結(jié)果圖
  • SCA124Hu.jpg 標(biāo)準(zhǔn)曲線(xiàn)圖
  • Certificate 通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

本試劑盒用于檢測(cè)轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1),經(jīng)檢測(cè)與其它相似物質(zhì)無(wú)明顯交叉反應(yīng)。
由于受到技術(shù)及樣本來(lái)源的限制,不可能完成對(duì)所有相關(guān)或相似物質(zhì)交叉反應(yīng)檢測(cè),因此本試劑盒有可能與未經(jīng)檢測(cè)的其它物質(zhì)有交叉反應(yīng)。

回收率

分別于定值血清及血漿樣本中加入一定量的轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)(加標(biāo)樣品),重復(fù)測(cè)定并計(jì)算其均值,回收率為測(cè)定值與理論值的比率。

樣本 回收率范圍(%) 平均回收率(%)
serum(n=5) 95-102 98
EDTA plasma(n=5) 85-101 91
heparin plasma(n=5) 83-98 89

精密度

精密度用樣品測(cè)定值的變異系數(shù)CV表示。CV(%) = SD/mean×100
批內(nèi)差:取同批次試劑盒對(duì)低、中、高值定值樣本進(jìn)行定量檢測(cè),每份樣本連續(xù)測(cè)定20 次,分別計(jì)算不同濃度樣本的平均值及SD值。
批間差:選取3個(gè)不同批次的試劑盒分別對(duì)低、中、高值定值樣本進(jìn)行定量測(cè)定,每個(gè)樣本使用同一試劑盒重復(fù)測(cè)定8次,分別計(jì)算不同濃度樣本的平均值及SD值。
批內(nèi)差: CV<10%
批間差: CV<12%

線(xiàn)性

在定值血清及血漿樣本內(nèi)加入適量的轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1),并倍比稀釋成1:2,1:4,1:8,1:16的待測(cè)樣本,線(xiàn)性范圍即為稀釋后樣本中轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)含量的測(cè)定值與理論值的比率。

樣本 1:2 1:4 1:8 1:16
serum(n=5) 87-101% 93-105% 84-98% 85-95%
EDTA plasma(n=5) 79-94% 96-105% 86-95% 79-91%
heparin plasma(n=5) 80-96% 81-89% 81-93% 93-101%

穩(wěn)定性

經(jīng)測(cè)定,試劑盒在有效期內(nèi)按推薦溫度保存,其活性降低率小于5%。
為減小外部因素對(duì)試劑盒破壞前后檢測(cè)值的影響,實(shí)驗(yàn)室的環(huán)境條件需盡量保持一致,尤其是實(shí)驗(yàn)室內(nèi)溫度、濕度及溫育條件。其次由同一實(shí)驗(yàn)員來(lái)進(jìn)行操作可減少人為誤差。

實(shí)驗(yàn)流程

1. 實(shí)驗(yàn)前標(biāo)準(zhǔn)品、試劑及樣本的準(zhǔn)備;
2. 加樣(標(biāo)準(zhǔn)品及樣本)100µL,37°C孵育1小時(shí);
3. 吸棄,加檢測(cè)溶液A100μL,37°C孵育1小時(shí);
4. 洗板3次;
5. 加檢測(cè)溶液B100µL,37°C孵育30分鐘;
6. 洗板5次;
7. 加底物100µL,37°C孵育10分鐘;
8. 讀數(shù)。

實(shí)驗(yàn)原理

將轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)抗體包被于96孔微孔板中,制成固相載體,向微孔中分別加入標(biāo)準(zhǔn)品或標(biāo)本,其中的轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)與連接于固相載體上的抗體結(jié)合,然后加入生物素化的轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)抗體,將未結(jié)合的生物素化抗體洗凈后,加入HRP標(biāo)記的親和素,再次徹底洗滌后加入底物。加入底物后會(huì)產(chǎn)生輝光型光信號(hào)。發(fā)射光強(qiáng)度和樣品中的轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)呈正相關(guān)。用化學(xué)發(fā)光儀測(cè)定相對(duì)光單位(RLU),計(jì)算樣品濃度。

相關(guān)產(chǎn)品

編號(hào) 適用物種:Homo sapiens (Human,人) 應(yīng)用(僅供研究使用,不用于臨床診斷!)
RPA124Hu02 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)重組蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
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EPA124Hu62 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)真核蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
EPA124Hu61 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)真核蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAA124Hu01 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)多克隆抗體 WB; IHC; ICC; IP.
LAA124Hu71 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)多克隆抗體(生物素標(biāo)記) WB; IHC; ICC.
LAA124Hu81 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)多克隆抗體(異硫氰酸熒光素標(biāo)記) WB; IHC; ICC; IF.
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MAA124Hu24 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 WB; IHC; ICC; IP.
MAA124Hu25 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 WB; IHC; ICC; IP.
RAA124Hu21 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)重組抗體 WB; IF; ICC; IHC; IP; FCM.
MAA124Hu27 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 WB; IHC; ICC; IP.
MAA124Hu29 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 WB; IHC; ICC; IP.
MAA124Hu21 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 WB; IHC; ICC; IP.
MAA124Hu26 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 WB; IHC; ICC; IP.
MAA124Hu28 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 WB; IHC; ICC; IP.
MAA124Hu22 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 WB; IHC; ICC; IP.
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SCA124Hu 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
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參考文獻(xiàn)

雜志 參考文獻(xiàn)
Cardiovascular Research Metformin attenuates cardiac fibrosis by inhibiting the TGFβ1–Smad3 signalling pathway [OxfordJournals: source]
Immunopharmacology and Inflammation Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid [ScienceDirect: S0188440910001049]
Biochemical and Biophysical Research Communications Chronic angiotensin-(1–7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-β/Smad signaling pathway in rabbits [ScienceDirect: S0006291X09017021]
European Cells and Materials Incorporating pTGF-β1/calcium phosphate nanoparticles with fibronectin into 3-dimensional collagen/chitosan scaffolds: efficient, sustained gene delivery to stem cells for chondrogenic differentiation. [Pubmed: 22314694]
Journal of Animal and Veterinary Advances A Soluble Antigen-Specific Factor from CD4+CD25+ T Cells of OVA Tolerant Mice Inducing OVA-Specific Peripheral Tolerance Independently in vivo [Medwell: 2011642650]
revue de medecine veterinaire Increased circulating concentrations of PDGF-BB and TGF-β1 in canine generalised demodicosis [Revmedvet: Source]
Biomedical and Environmental Sciences The Intervention Effect of Rosiglitozone in Ovarian Fibrosis of PCOS Rats [Besjournal: Source]
The Open Respiratory Medicine Journal Biomarkers of Fibroproliferative Healing in Fibrosing Idiopathic Interstitial Pneumonias [PubMed: PMC3551240]
PLoS ONE A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches [Plosone: Source]
J Physiol Pharmacol. Fibrogenic response of hepatic stellate cells in ovarectomised rats exposed to ketogenic diet [Pubmed: 23568967]
international Journal of food and nutritional sciences EVALUATION OF PHYSICO-CHEMICAL PROPERTIES OF COLOSTRUM SUPPLEMENTED DAHI [Ijfans: Source]
Journal of ethnopharmacology Multitargeted protective effect of Abacopteris penangiana against carrageenan-induced chronic prostatitis in rats. [Pubmed: 24211397]
Int J Clin Exp Pathol Development of a KLD-12 polypeptide/TGF-β1-tissue scaffold promoting the differentiation of esenchymal stem cell into nucleus pulposus-like cells for treatment of intervertebral disc degeneration [Ijcep:Source]
Am J Physiol Regul Integr Comp Physiol. Prolactin anterior pituitary expression and circulating levels are reduced in obese and diabetic rats: Role of TGFβ and TNFα [Pubmed:25715833]
Exp Ther Med. PAR2, IL4R, TGFβ and TNFα in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosis [Pubmed:Pmc4079423]
International Journal of Molecular Medicine Effect of combined treatment with rosuvastatin and protein kinase Cβ2 inhibitor on angiogenesis following myocardial infarction in diabetic rats [Pubmed:25524396]
Indian J Pharmacol Effect of coenzyme Q10 alone and its combination with metformin on streptozotocin-nicotinamide-induced diabetic nephropathy in rats [Pubmed:25538335]
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis [Pubmed:25541279]
Anadolu Kardiyol Derg. A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes. [Pubmed:25592103]
Journal of Drug Targeting Apoptosis, Advanced Glycation End Products and Transforming Growth Factor-β1 by Biguanides and Resveratrol to Ameliorate Experimentally-induced Diabetic Nephropathy [Pdf: Drugs]
Mol Med Rep NIM811 downregulates transforming growth factor [PubMed: 26573209]
The Tohoku Journal of Experimental Medicine Salvia Miltiorrhiza Bge.f.alba Ameliorates the Progression of Monocrotaline-Induced Pulmonary Hypertension by Protecting Endothelial Injury in Rats [PubMed: 26074502]
Oncol Rep Therapeutic effects of bone marrow-derived mesenchymal stem cells on radiation-induced lung injury [PubMed: 26717975]
J Surg Res Epigallocatechin-3-gallate reduces tubular cell apoptosis in mice with ureteral obstruction [PubMed: 25913488]
Histol Histopathol Estrogen-deficient osteoporosis enhances the recruitment and activity of osteoclasts by breast cancer cells [PubMed: 26254457]
Clin Exp Pharmacol Physiol Silymarin attenuates paraquat-induced lung injury via Nrf2-mediated pathway in vivo and in vitro [PubMed: 26173462]
Immunologic Research Mesenchymal stromal cell-dependent reprogramming of Kupffer cells is mediated by TNF-α and PGE6 and is crucial for liver transplant tolerance [PubMed: 25982596]
Journal of Neuroscience MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination [PubMed: 25904788]
J Reprod Immunol The immunomodulating effect of seminal plasma on T cells [PubMed: 25799173]
Nutr Cancer Camel Milk: Potential Utility as an Adjunctive Therapy to Peg-IFN/RBV in HCV-4 Infected Patients in Egypt [PubMed: 26492130]
Int J Clin Exp Med Uighur medicine abnormal savda munzip (ASMq) suppresses expression of collagen and TGF-β1 with concomitant induce Smad7 in human hypertrophic scar … [PubMed: 26309506]
Int J Clin Exp Pathol Development of a KLD-12 polypeptide/TGF-β1-tissue scaffold promoting the differentiation of mesenchymal stem cell into nucleus pulposus-like cells for treatment of intervertebral disc degeneration. [PubMed: 25972996]
International Immunopharmacology Oxymatrine attenuates CCl 4-induced hepatic fibrosis via modulation of TLR4-dependent inflammatory and TGF-β1 signaling pathways [Pubmed:27179304]
Deletion Polymorphism and Chronic Obstructive Pulmonary Disease ReCavia (Guinea pig )lation of Viral Infection-induced Airway Remodeling Cytokine Production by the TLR3-EGFR Signaling Pathway in Human Bronchial Epithelial Cells [Pubmed:27075970]
Tissue and Cell Human umbilical cord blood-mesenchymal stem cells transplantation renovates the ovarian surface epithelium in a rat model of premature ovarian failure: Possible direct and indirect effects [Pubmed:27233913]
Cancer Medicine & Anti Cancer Drugs Ameliorative Potential of Tamoxifen/Thymoquinone Combination in Patients with Breast Cancer: A Biochemical and Immunohistochemical Study [open-access:1000102]
Sleep Sciences Th17 Cell Related Cytokine Profiles in Narcolepsy and Other Types of Excessive Daytime Sleepiness [article:15]
Tissue Cell. Ameliorative potential of fluoxetine/raloxifene combination on experimentally induced breast cancer [Pubmed:26881735]
International Journal of Molecular Sciences TGF-β and Physiological Root Resorption of Deciduous Teeth. [pubmed:28035998]
BMC Veterinary Research Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis [pubmed:27553600]
immunology letters Recombinant Mip-PilE-FlaA dominant epitopes vaccine candidate against Legionella pneumophila. [pubmed:28366526]
immunology letters Gemcitabine treatment enhanced the anti-tumor effect of cytokine induced killer cells by depletion of CD4+CD25bri regulatory T cells. [pubmed:27867030]
Journal of Cardiovascular Electrophysiology Effect of Cardiac Resynchronization Therapy on Myocardial Fibrosis and Relevant Cytokines in a Canine Model With Experimental Heart Failure. [pubmed:28127817]
Molecular Medicine Reports The?protective?role?of?vitamin?D3?in a?murine?model?of?asthma?via?the?suppression?of TGF-β/Smad?signaling?and?activation?of the?Nrf2/HO-1?pathway. [pubmed:27484042]
International Immunopharmacology Amelioration of bleomycin-induced lung fibrosis in rats by valproic acid and butyrate: Role of nuclear factor kappa-B, proinflammatory cytokines and oxidative stress [pubmed:27526269]
Cellular?Physiology and Biochemistry Renal Denervation Attenuates Multi-Organ Fibrosis and Improves Vascular Remodeling in Rats with Transverse Aortic Constriction Induced Cardiomyopathy [pubmed:27889753]
Canadian Journal of Physiology and Pharmacology The effect of midkine on growth factors and oxidative status in an experimental wound model in diabetic and healthy rats [pubmed:28177680]
PLoS One. Differential frequency of CD8+ T cell subsets in multiple sclerosis patients with various clinical patterns [pubmed:27467597]
Therapeutics?and?Clinical?Risk?Management Elevated?blood?plasma?levels?of?epinephrine,?norepinephrine,?tyrosine?hydroxylase, TGFβ1, and TNFα?associated?with?high-altitude?pulmonary?edema?in an Indian population. [pubmed:27540296]
Journal of Cancer Research and Treatment Effect of Indole-3-carbinol and/or Metformin on Female Patients with Ulcerative Colitis (Premalignant Condition): Role of Oxidative Stress, Apoptosis and Proinflammatory Cytokines [jcrt:5]
Sci Rep Follistatin like-1 aggravates silica-induced mouse lung injury [PMC5428474]
Ren Fail.? Effect of concomitant administration of coenzyme Q10 with sitagliptin on experimentally induced diabetic nephropathy in rats. [pubmed:27841100]
Basic Clin Pharmacol Toxicol. Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4+ T Helper 17 (Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling. [pubmed:28032440]
Acta Vet Hung. Imbalance of intestinal immune function in piglets infected by porcine circovirus type 2 during the fetal period. [pubmed:28244338]
Gut Pathog. Oral administration of Clostridium butyricum CGMCC0313‐1 reduces ovalbumin‐induced allergic airway inflammation in mice [pubmed:28250847]
Environmental Toxicology and Pharmacology Ameliorative potential of linagliptin and/or calcipotriol on bleomycin-induced lung fibrosis: In vivo and in vitro study [pubmed:28192751]
PeerJ Platelet-rich concentrate in serum free medium enhances osteogenic differentiation of bone marrow-derived human mesenchymal stromal cells [pubmed:27651984]
Biomedical and Environmental Sciences Crystalline Silica Promotes Rat Fibrocyte Differentiation?in Vitro, and Fibrocytes Participate in Silicosis?in Vivo [pubmed:29081339]
Toxicology and Applied Pharmacology Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) [pubmed:28974454]
Oral Diseases Glucosamine oral administration as an adjunct to hyaluronic acid injection in treating temporomandibular joint osteoarthritis [pubmed:28862770]
Biomedicine & Pharmacotherapy Cytokine production in vitro and in rat model of colitis in response to Lactobacillus plantarum LS/07 [pubmed:28830068]
Research in Veterinary Science The effect of feed supplementation with effective microorganisms(EM) on pro- and anti-inflammatory cytokine concentrations in pigs [pubmed:28549299]
Journal of Materials Chemistry B Extracellular Matrix Powder from Cultured Cartilage-Like Tissue as Cell Carriers for Cartilage Repair [DOI:10.1039/C7TB00640C]
National Natural Scientific Role of Gut-Derived Endotoxin on Type I Collagen Production in the Rat Pancreas after Chronic Alcohol Exposure [pubmed:29121396]
Basic & Clinical Pharmacology & Toxicology Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4 + T Helper 17(Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling [doi:10.1111]
Experiental And Therapeutic Medicine Plasma proteins as potential targets of abnormal Savda syndrome in asthma patients treated with unique Uighur prescription [pubmed:28672924]
Oncotarget. Tumor-associated macrophages promote tumor metastasis via the TGF-β/SOX9 axis in non-small cell lung cancer [pubmed:29245941]
International Journal of Chemical Studies Studies on quality attributes of skimmed colostrum powder [P-ISSN: 2349–8528]
Scientific RepoRts Follistatin like-1 aggravates silicainduced mouse lung injury [pubmed:28341862]
Evidence-Based Complementary and Alternative Medicine Cardioprotection against Heart Failure by Shenfu Injection via TGF-β/Smads Signaling Pathway [pubmed:28698735]
Molecular Medicine Reports Pigment epithelium?derived factor protects human glomerular mesangial cells from diabetes via NOXO1?iNOS suppression [10.3892/mmr.2017.7563]
ARTIFICIAL?CELLS?NANOMEDICINE AND BIOTECHNOLOGY? Dexamethasone reduces serum level of IL-17 in Bleomycin-A5-induced rats model of pulmonary fibrosis [pubmed:28608724]
Cell Physiol Biochem Exendin-4 Induces Bone Marrow Stromal Cells Migration Through Bone Marrow-Derived Macrophages Polarization via PKA-STAT3 Signaling Pathway [pubmed:29216639]
Chemico-biological Interactions The promising effect of linagliptin and/or indole-3-carbinol on experimentally-induced polycystic ovarian syndrome. [pubmed:28619389]
PLoS One Protective effect of aplysin on liver tissue and the gut microbiota in alcohol-fed rats [pubmed:28622357]
Evidence-based complementary and alternative medicine Qiliqiangxin Enhances Cardiac Glucose Metabolism and Improves Diastolic Function in Spontaneously Hypertensive Rats [pubmed:28706558]
Molecular and Cellular Neuroscience TGF-β1 enhances phagocytic removal of neuron debris and neuronal survival by olfactory ensheathing cells via integrin/MFG-E8 signaling pathway [10.1016/j.mcn.2017.08.006]
Journal of?Thoracic?Oncology Systemic and Tumor Th1 and Th2 Inflammatory Profile and Macrophages in Lung Cancer: Influence of Underlying Chronic Respiratory Disease. [pubmed:27793775]
Journal?of?Controlled?Release Nose-to-brain delivery of insulin enhanced by a nanogel carrier [Pubmed:29196041]
Journal of?Cellular?And Molecular?Medicine? Lipopolysaccharide enhances TGF‐β1 signalling pathway and rat pancreatic fibrosis [Pubmed:29424488]
International Journal of Biochemistry &?Cell?Biology Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling [Pubmed:29940125]
Physiology &?Behavior? Linagliptin potentiates the effect of l-dopa on the behavioural, biochemical and immunohistochemical changes in experimentally-induced Parkinsonism: Role of toll?… [Pubmed:29410018]
Journal of Molecular Neuroscience A Novel scFv Anti-Aβ Antibody Reduces Pathological Impairments in APP/PS1 Transgenic Mice via Modulation of Inflammatory Cytokines and Aβ-related Enzymes [Pubmed:30062438]
Oncotarget Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy [Pubmed:29423092]
Oncotarget Hypoxia-inducible factor-1α activates transforming growth factor-β1/Smad signaling and increases collagen deposition in dermal fibroblasts [Pubmed:29423039]
Communications Biology Activated hepatic stellate cells promote epithelial-to-mesenchymal transition in hepatocellular carcinoma through transglutaminase 2-induced pseudohypoxia []
Bulletin?of Experimental?Biology?and?Medicine Expression of Hif-1α, Nf-κb, and Vegf Genes in the Liver and Blood Serum Levels of HIF-1α, Erythropoietin, VEGF, TGF-β, 8-Isoprostane, and Corticosterone in Wistar Rats with High and Low Resistance to Hypoxia. Corticosterone in?… [Pubmed: 30353332]
Phytomedicine Mechanistic insights to the cardioprotective effect of Blueberry Nutraceutical Extract in Isoprenaline-Induced Cardiac Hypertrophy []
Veterinary?Immunology?and?Immunopathology Evaluation of T regulatory lymphocytes and serum concentration of selected cytokines in dogs with perianal tumors []
Experimental?and Therapeutic Medicine Rhynchophylline attenuates allergic bronchial asthma by inhibiting transforming growth factor?β1?mediated Smad and mitogen?activated protein kinase signaling?… []
Biology?of?Reproduction Recombinant adiponectin alleviates abortion in mice by regulating Th17/Treg imbalance via p38MAPK-STAT5 pathway [Pubmed: 30496353]
International Journal of Peptide Research and Therapeutics ANP/NPRA Inhibits Epithelial-Mesenchymal Transition of Airway by Targeting Smad3 in Asthma []
Journal of?Neuroinflammation Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer's disease [Pubmed: 30777084]
Biochimie Periostin contributes to renal and cardiac dysfunction in rats with chronic kidney disease: reduction of PPARα [Pubmed: 30890453]
Molecular?Medicine?Reports Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction [Pubmed: 30816496]
International Journal of?Nanomedicine Improving the anti-keloid outcomes through liposomes loading paclitaxel–cholesterol complexes [Pubmed: 30863067]
Behavioural Brain Research THE ROLE OF ANTI-INFLAMMATORY CYTOKINES IN MEMORY PROCESSING IN A HEALTHY BRAIN []
International Journal of Ophthalmology A novel xeno-free culture system for human retinal pigment epithelium cells [Pubmed: 31024807]
Open Access Macedonian Journal of Medical Sciences Low Degree Hyaluronic Acid Crosslinking Inducing the Release of TGF-Β1 in Conditioned Medium of Wharton's Jelly-Derived Stem Cells []
中國(guó)免疫學(xué)雜志 TRAF-6 調(diào)控TGF-β1-Smad2/Smad3 信號(hào)通路在Graves 病免疫發(fā)病機(jī)制中的作用 []
Food & Function Network pharmacology oriented study reveals inflammatory state-dependent dietary supplement hepatotoxicity responses in normal and diseased rats [Pubmed: 31140472]
Annals of clinical and laboratory science CD19+ CD24hiCD38hi Regulatory B cells Involved in Hepatic Alveolar Hydatid Infection in Humans [Pubmed: 31308033]
Life sciences Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation [Pubmed: 31254585]
Acta Histochemica Hyperoside protects against heart failure-induced liver fibrosis in rats [Pubmed: 31353051]
Cardiology Circulating Connective Tissue Growth Factor Is Associated with Diastolic Dysfunction in Patients with Diastolic Heart Failure [Pubmed: 31466059]
Scientific Reports Anti-inflammatory and antioxidant effects of muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus [Pubmed: 31578381]
toxicology and applied pharmacology miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1 [Pubmed: 31734320]
Experimental Cell Research CD4+ CD25+ Tregs as dependent factor in the course of bleomycin-induced pulmonary fibrosis in mice [Pubmed: 31678213]
Prostaglandins & other Lipid Mediators Lipoxin A4 inhibited the activation of Hepatic Stellate Cells-T6 cells by modulating profibrotic cytokines and NF-κB signaling pathway [Pubmed: 31698141]
International Journal of Rheumatic Diseases Effects of thalidomide on Th17, Treg cells and TGF‐β1/Smad3 pathway in a mouse model of systemic sclerosis [Pubmed: 31840939]
Pigment Cell & Melanoma Research Altered expression of nuclear factor of activated T cells, Forkhead Box P3 and immune suppressive genes in regulatory T cells of generalized vitiligo patients [Pubmed: 31917889]
Cell Communication and Signaling Rapamycin promotes endothelial–mesenchymal transition during stress-induced premature senescence through the activation of autophagy [Pubmed: 32164764]
Biomed Pharmacother Soufeng Yuchuan decoction mitigates the ovalbumin-induced lung damage in a rat model of asthma [Pubmed: 32036215]
Biochemical and Biophysical Research Communications Isorhynchophylline exerts anti-asthma effects in mice by inhibiting the proliferation of airway smooth muscle cells: The involvement of miR-200a-mediated FOXC1/NF?… [Pubmed: 31733831]
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vitamin D Attenuates Loss of Endothelial Biomarker Expression in Cardio-Endothelial Cells [Pubmed: 32235811]
Journal of Oral Biology and Craniofacial Research Levels of TGF-β1 in peri-miniscrew implant crevicular fluid [Pubmed: 32211284]
Acta Histochem Paeoniflorin accelerates foot wound healing in diabetic rats though activating the Nrf2 pathway [Pubmed: 33166863]
EUROPEAN JOURNAL OF PHARMACOLOGY The anti-asthmatic potential of flavonol kaempferol in an experimental model of allergic airway inflammation [Pubmed: 33122672]
Journal of Cosmetic Dermatology Examination of androgenetic alopecia with serum biomarkers [Pubmed: 32969583]
MOLECULAR AND CELLULAR BIOCHEMISTRY Soluble recombinant human thrombomodulin suppresses inflammation-induced gastrointestinal tumor growth in a murine peritonitis model [Pubmed: 32767229]
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY Hepatoprotective effect of Linagliptin against liver fibrosis induced by carbon tetrachloride in mice [Pubmed: 32726558]
EXPERIMENTAL DERMATOLOGY Decreased suppression of CD8+ and CD4+ T cells by peripheral Regulatory T cells in Generalized Vitiligo due to reduced NFATC1 and FOXP3 proteins [Pubmed: 32682346]
Scientific Reports Erlotinib can halt adenine induced nephrotoxicity in mice through modulating ERK1/2, STAT3, p53 and apoptotic pathways [Pubmed: 32661331]
international journal of biological macromolecules Chlorella vulgaris α-L-arabino-α-L-rhamno-α, β-D-galactan structure and mechanisms of its anti-inflammatory and anti-remodelling effects [Pubmed: 32565301]
Exp Cell Res Exosomal miR-532–5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5 [Pubmed: 32464126]
JOURNAL OF IMMUNOLOGY RESEARCH The Sufficient Immunoregulatory Effect of Autologous Bone Marrow-Derived Mesenchymal Stem Cell Transplantation on Regulatory T Cells in Patients with … [Pubmed: 32411794]
Frontiers in Pharmacology M10, a Myricetin-3-ObD-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice [Pubmed: 33041798]
Food & Function Nicotinamide riboside alleviates alcohol-induced depression-like behaviours in C57BL/6J mice by altering the intestinal microbiota associated with microglial?… []
Effect of metformin and indole-3-carbinol on a rat model of Parkinson's disease induced by 6-hydroxydopamine []
Research square Vitamin D Status in Dupuytren's Disease: Association with Clinical Status and Vitamin D Receptor Expression []
Phytomedicine Menthacarin attenuates experimental colitis []
Immunomodulatory effects of sCD83 via induction of TGF-β1 and IDO: an in vitro and rat orthotopic liver transplantation study []
BMC Complement Med Ther Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma [33413331]
Life Sci Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats [33577848]
CLINICAL SCIENCE Berberine accelerated wound healing by restoring TrxR1/JNK in diabetes [33491733]
Bioact Mater New design to remove leukocytes from platelet-rich plasma (PRP) based on cell dimension rather than density [33842739]
Acta Biomater Highly interconnected inverse opal extracellular matrix scaffolds enhance stem cell therapy in limb ischemia [33878473]
Mol Cell Biochem Human umbilical cord-derived mesenchymal stem cells and their chondroprogenitor derivatives reduced pain and inflammation signaling and promote regeneration in??- [33864569]
Cell Death & Disease Sodium/glucose cotransporter 1-dependent metabolic alterations induce tamoxifen resistance in breast cancer by promoting macrophage M2 polarization [34006822]
PLoS One Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment?aIn vivo studies [33999928]
Vascular pharmacology Nectin-4 promotes lymphangiogenesis and lymphatic metastasis in breast cancer by regulating CXCR4-LYVE1 axis [33945869]
Equine Vet J Limited added value of negative pressure wound therapy compared to calcium alginate dressings for second intention healing in a non?\contaminated and??- [34115409]
Stem Cells International The Paracrine Effect of Adipose-Derived Stem Cells Orchestrates Competition between Different Damaged Dermal Fibroblasts to Repair UVB-Induced Skin??- [33381190]
Journal of Pharmacy and Pharmacology Pharmacodynamic evaluation of dihydroxyflavone derivate chrysin in a guinea pig model of allergic asthma [33793800]
Bull. Egypt. Soc. Physiol. Sci. Flaxseed Oil Supplementation Afford Comparable Therapeutic effect to Metformin in Bleomycin Induced Pulmonary Fibrosis Rat model []
D£?ˉ Role of Angiotensin II and Renal Nerves on TGF-b/SmadPathway in Diabetic Nephropathy Rat Model []
Bioactive Materials Calcium phosphate-based materials regulate osteoclast-mediated osseointegration []
Mediators of Inflammation Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the Activity of |á1, 3 ?- []
Manuscript title Microparticles Containing MiR-625-5p In Coronary Artery Reduce Myocardial Fibrosis After Myocardial Infarction []
Andrology X‐ray micro‐computed tomography in the assessment of penile cavernous fibrosis in a rabbit castration model [34236146]
Aging Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular?… [34315133]
Tissue Eng Regen Med Effect of Leukocyte-Platelet Rich Fibrin (L-PRF) on Tissue Regeneration and Proliferation of Human Gingival Fibroblast Cells Cultured Using a Modified Method [34339025]
Am J Transl Res Wuling San and Xiao Chaihu Decoction affect airway inflammatory response and airway smooth muscle cell proliferation in mice with allergic asthma via miR?… [34786062]
Biomacromolecules In Situ Forming Cellulose Nanofibril-Reinforced Hyaluronic Acid Hydrogel for Cartilage Regeneration [34723499]
Brain Sci Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial?… [34942919]
Biomedicines Exploring Epithelial–Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes [34829910]
J Inflamm Res Clenbuterol, a Selective β2-Adrenergic Receptor Agonist, Inhibits or Limits Post-Stroke Pneumonia, but Increases Infarct Volume in MCAO Mice [Pubmed:35058704]
Cancer Commun (Lond) Anti‐PD‐L1/TGF‐βR fusion protein (SHR‐1701) overcomes disrupted lymphocyte recovery‐induced resistance to PD‐1/PD‐L1 inhibitors in lung cancer [Pubmed:34981670]
Polymers (Basel) 3D Printed Scaffold Based on Type I Collagen/PLGA_TGF-β1 Nanoparticles Mimicking the Growth Factor Footprint of Human Bone Tissue [Pubmed:35267680]
Biomed Pharmacother Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis [Pubmed:35453007]
Biomed Pharmacother Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats [Pubmed:35430394]
Antioxidants Bio-Evaluation of the Wound Healing Activity of Artemisia judaica L. as Part of the Plant's Use in Traditional Medicine; Phytochemical, Antioxidant, Anti-Inflammatory?… [Pubmed:35204215]
Frontiers in Molecular Neuroscience Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines [Pubmed:35465093]
Vaccines Age-Dependent Dynamics of Maternally Derived Antibodies (MDAs) and Understanding MDA-Mediated Immune Tolerance in Foot-and-Mouth Disease-Vaccinated?… [Pubmed:35632433]
Biomaterials Advances Human adipose-derived stem cell-loaded small intestinal submucosa as a bioactive wound dressing for the treatment of diabetic wounds in rats []
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