肥大細(xì)胞類糜蛋白酶1(CMA1)重組蛋白
Recombinant Chymase 1, Mast Cell (CMA1)
CYH; CYM; Alpha-chymase; Mast cell protease I
- 編號(hào)RPG515Hu01
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位分泌, 細(xì)胞質(zhì)
- 預(yù)測(cè)分子量28.7kDa
- 實(shí)際分子量29kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
- 片段與標(biāo)簽Ile22~Asn247 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液，（pH8.0,含有1mM EDTA, 1mM DTT, 0.01%skl, 5% Trehalose and Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點(diǎn)9.6
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載 英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure . Gene Sequencing (extract)
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Figure. SDS-PAGE
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通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPG515Hu01 | 肥大細(xì)胞類糜蛋白酶1(CMA1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAG515Hu01 | 肥大細(xì)胞類糜蛋白酶1(CMA1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAG515Hu02 | 肥大細(xì)胞類糜蛋白酶1(CMA1)多克隆抗體 | WB; IHC; ICC; IP. |
| MAG515Hu21 | 肥大細(xì)胞類糜蛋白酶1(CMA1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEG515Hu | 肥大細(xì)胞類糜蛋白酶1(CMA1)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMG515Hu | 肥大細(xì)胞類糜蛋白酶1(CMA1)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Pathobiology | Anti-Angiotensin and Hypoglycemic Treatments Suppress Liver Metastasis of Colon Cancer Cells [Karger: 000330169] |
| Clinical and Experimental Metastasis | Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer [PubMed: 22552372] |
| Mediators of Inflammation | Mediators of Mast Cells in Bullous Pemphigoid and Dermatitis Herpetiformis [Pubmed:25400334] |
| Neurogastroenterology & Motility | Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery [Pubmed:25677271] |
| IJC Metab Endocr | The autocrine role of tryptase in pressure overload-induced mast cell activation, chymase release and cardiac fibrosis [PubMed: 26722642] |
| Journal of?Neuroinflammation | Oral sensitization to whey proteins induces age-and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food?… [Pubmed:29685134] |
| Revista do Instituto de Medicina Tropical de S?o Paulo | Vasoactive intestinal peptide degradation might influence Interleukin-17 expression in cardiac chagasic patients [Pubmed: 30365640] |
| Science Advances | Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury [Pubmed: 32206714] |
| Immunity Inflammation and Disease | Disruption in the balance between apolipoprotein A‐I and mast cell chymase in chronic hypersensitivity pneumonitis [Pubmed: 33016012] |
| Microbiol Spectr | Mast Cell-Derived Proteases Induce Endothelial Permeability and Vascular Damage in Severe Fever with Thrombocytopenia Syndrome [Pubmed:35612327] |
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