顆粒酶B(GZMB)真核蛋白
Eukaryotic Granzyme B (GZMB)
GZM-B; HLP; CTLA1; CCPI; CGL1; CSP-B; CSPB; CTSGL1; SECT; Granzyme 2; Cytotoxic T-Lymphocyte-Associated Serine Esterase 1; Fragmentin 2; Cytotoxic Serine Protease B
- 編號EPA600Ra62
- 物種Rattus norvegicus (Rat,大鼠) 相同的名稱,不同的物種。
- 來源真核表達
- 宿主293F cell
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌, 溶酶體
- 預測分子量56.4kDa
- 實際分子量65kDa(差異分析請參閱說明書)
- 片段與標簽Gly19~Ser248 with N-terminal His Tag and C-terminal Fc Region of Human IgG1
- 緩沖液成份PBS, pH7.4, containing 5% Trehalose.
- 性狀凍干粉
- 純度> 80%
- 等電點10.1
-
應用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 暫無報價 暫無報價 暫無報價 暫無報價 暫無報價
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序列
用法
Reconstitute in ddH2O to a concentration less than or equal to 0.1mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月,-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當?shù)臈l件下存儲,損失率低于5%。
增值服務
相關(guān)產(chǎn)品
編號 | 適用物種:Rattus norvegicus (Rat,大鼠) | 應用(僅供研究使用,不用于臨床診斷!) |
RPA600Ra01 | 顆粒酶B(GZMB)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
EPA600Ra62 | 顆粒酶B(GZMB)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAA600Ra01 | 顆粒酶B(GZMB)多克隆抗體 | WB; IHC; ICC; IP. |
MAA600Ra21 | 顆粒酶B(GZMB)單克隆抗體 | WB; IHC; ICC; IP. |
SEA600Ra | 顆粒酶B(GZMB)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMA600Ra | 顆粒酶B(GZMB)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
雜志 | 參考文獻 |
International Journal of Cancer | Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70 [Pubmed:24691976] |
Biol Pharm Bull. | Z-100, an Immunomodulatory Extract of Mycobacterium tuberculosis Strain Aoyama B, Prevents Spontaneous Lymphatic Metastasis of B16-BL6 Melanoma [Pubmed:24818259] |
Journal of Dermatological Science | Relationships?among?plasma?granzyme?B?level,?pruritus?and?dermatitis?in?patients?with?atopicdermatitis. [pubmed:27686401] |
Oncotarget | Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment [Pubmed:29983866] |
Theranostics | A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors [Pubmed: 31695790] |
Am J Transl Res | Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma [34377237] |
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