肝素結(jié)合性表皮生長因子(HBEGF)真核蛋白
Eukaryotic Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)
HB-EGF; DTR; DTS; DTSF; HEGFL; Diphtheria Toxin Receptor; Proheparin-binding EGF-like growth factor; Diphtheria toxin receptor
- 編號EPB479Hu61
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源真核表達
- 宿主293F cell
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位細胞膜, 分泌
- 預(yù)測分子量17.2kDa
- 實際分子量18kDa(差異分析請參閱說明書)
- 片段與標簽Val21~Thr160 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 90%
- 等電點9.7
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價格 ¥ 1008 ¥ 2520 ¥ 5040 ¥ 15120 ¥ 37800
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| APB479Hu01 | 肝素結(jié)合性表皮生長因子(HBEGF)活性蛋白 | Cell?culture;?Activity?Assays. |
| APB479Hu61 | 肝素結(jié)合性表皮生長因子(HBEGF)活性蛋白 | Cell?culture;?Activity?Assays. |
| EPB479Hu61 | 肝素結(jié)合性表皮生長因子(HBEGF)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB479Hu01 | 肝素結(jié)合性表皮生長因子(HBEGF)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB479Hu01 | 肝素結(jié)合性表皮生長因子(HBEGF)多克隆抗體 | WB,IHC |
| LAB479Hu71 | 肝素結(jié)合性表皮生長因子(HBEGF)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| MAB479Hu22 | 肝素結(jié)合性表皮生長因子(HBEGF)單克隆抗體 | WB; IHC; ICC; IP. |
| MAB479Hu25 | 肝素結(jié)合性表皮生長因子(HBEGF)單克隆抗體 | WB; IHC; ICC; IP. |
| MAB479Hu21 | 肝素結(jié)合性表皮生長因子(HBEGF)單克隆抗體 | WB; IHC; ICC; IP. |
| MAB479Hu23 | 肝素結(jié)合性表皮生長因子(HBEGF)單克隆抗體 | WB; IHC; ICC; IP. |
| MAB479Hu24 | 肝素結(jié)合性表皮生長因子(HBEGF)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB479Hu | 肝素結(jié)合性表皮生長因子(HBEGF)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB479Hu | 肝素結(jié)合性表皮生長因子(HBEGF)檢測試劑盒(化學發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMB479Hu | 肝素結(jié)合性表皮生長因子(HBEGF)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Neuropathology | Astrocyte ERK phosphorylation precedes K+-induced swelling but follows hypotonicity-induced swelling. [PubMed: 21118399] |
| Toxicological Sciences | Cypermethrin Induces Astrocyte Apoptosis by the Disruption of the Autocrine/Paracrine Mode of Epidermal Growth Factor Receptor Signaling [Pubmed: source] |
| PAIN RESEARCH | 軽度炎癥性膀胱痛マウスモデルの構(gòu)築とNGFの関與 [Jstage:Source] |
| European Journal of Pain | A?novel?method?for?assessing?bladder-related?pain?reveals?the?involvement?of?nerve?growth?factor?in?painassociated?with?cyclophosphamide-induced?chronic?cystitis?in?mice. [Pubmed:25820250] |
| Kinki daigaku | 2 型糖尿病モデルラットにおける糖尿病性腎癥の進行とHB-EGF の関連性 [17844] |
| laboratory investigation | Heparin-binding epidermal growth factor contributes to COPD disease severity by modulating airway fibrosis and pulmonary epithelial–mesenchymal transition [Pubmed:29581578] |
| International Journal of Biological Sciences | CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17 [] |
| Redox?Biology | Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth [Pubmed: 30769285] |
| JOURNAL OF CELLULAR AND MOLECULAR MEDICINE | Polarization of ADAM17‐driven EGFR signalling in electric field‐guided collective migration of epidermal sheets [Pubmed: 33164313] |
| 象牙芽細胞の枯渇は象牙芽細胞分化と象牙質(zhì)形成を誘導する [] |
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