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成纖維細(xì)胞生長因子23(FGF23)重組蛋白

Recombinant Fibroblast Growth Factor 23 (FGF23)

ADHR; HYPF; HPDR2; PHPTC; Phosphatonin; Tumor-derived hypophosphatemia-inducing factor

編號(hào)RPA746Hu01
物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 所有
- 人
- 小鼠
- 大鼠
- 豚鼠
- 家兔
- 獼猴
- 山羊
- 綿羊
- 馬
- 牛
- 豬
- 雞
- 狗
- 其他物種
- 多物種
- 泛物種
來源原核表達(dá)
宿主E.coli
內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
亞細(xì)胞定位分泌
預(yù)測(cè)分子量12.9kDa
實(shí)際分子量14kDa(差異分析請(qǐng)參閱說明書)
片段與標(biāo)簽Ala24~Val126 with N-terminal His Tag
緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
性狀凍干粉
純度> 95%
等電點(diǎn)7.2
應(yīng)用 Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見活性蛋白。
下載英文說明書中文說明書
規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)

SDS-PAGE圖

通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

序列

用法

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

儲(chǔ)存

避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。

贈(zèng)品

聚丙烯酰胺凝膠電泳(PAGE)實(shí)驗(yàn)服務(wù)

增值服務(wù)

去內(nèi)毒素試劑盒
 BCA蛋白定量檢測(cè)試劑盒
 蛋白標(biāo)記定制服務(wù)
蛋白分子量MARKER
重組蛋白定制服務(wù)
單克隆抗體定制服務(wù)
多克隆抗體定制服務(wù)
蛋白活性測(cè)定實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
緩沖液
 內(nèi)毒素去除試劑盒Ⅱ
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
棘突蛋白受體結(jié)合結(jié)構(gòu)域
 蛋白G
蛋白 A

相關(guān)產(chǎn)品

編號(hào)	適用物種：Homo sapiens (Human，人)	應(yīng)用(僅供研究使用，不用于臨床診斷！)
RPA746Hu01	成纖維細(xì)胞生長因子23(FGF23)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA746Hu02	成纖維細(xì)胞生長因子23(FGF23)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA746Hu03	成纖維細(xì)胞生長因子23(FGF23)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
APA746Hu03	成纖維細(xì)胞生長因子23(FGF23)活性蛋白	Cell?culture;?Activity?Assays.
RPA746Hu04	成纖維細(xì)胞生長因子23(FGF23)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
APA746Hu01	成纖維細(xì)胞生長因子23(FGF23)活性蛋白	Cell?culture;?Activity?Assays.
PAA746Hu02	成纖維細(xì)胞生長因子23(FGF23)多克隆抗體	WB,IHC.
PAA746Hu03	成纖維細(xì)胞生長因子23(FGF23)多克隆抗體	WB; IHC; ICC; IP.
PAA746Hu04	成纖維細(xì)胞生長因子23(FGF23)多克隆抗體	WB; IHC; ICC; IP.
PAA746Hu01	成纖維細(xì)胞生長因子23(FGF23)多克隆抗體	WB; IHC; ICC; IP.
LAA746Hu71	成纖維細(xì)胞生長因子23(FGF23)多克隆抗體(生物素標(biāo)記)	WB; IHC; ICC.
RAA746Hu21	成纖維細(xì)胞生長因子23(FGF23)重組抗體	WB; IF; ICC; IHC; IP; FCM.
MAA746Hu23	成纖維細(xì)胞生長因子23(FGF23)單克隆抗體	WB; IHC; ICC; IP.
MAA746Hu22	成纖維細(xì)胞生長因子23(FGF23)單克隆抗體	WB; IHC; ICC; IP.
MAA746Hu21	成纖維細(xì)胞生長因子23(FGF23)單克隆抗體	WB; IHC; ICC; IP.
LAA746Hu72	成纖維細(xì)胞生長因子23(FGF23)單克隆抗體(生物素標(biāo)記)	WB; IHC; ICC.
MEA746Hu	成纖維細(xì)胞生長因子23(FGF23)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,小樣本)	Enzyme-linked immunosorbent assay for Antigen Detection.
SEA746Hu	成纖維細(xì)胞生長因子23(FGF23)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMA746Hu	成纖維細(xì)胞生長因子23(FGF23)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)	FLIA Kit for Antigen Detection.

參考文獻(xiàn)

雜志	參考文獻(xiàn)
Journal of international medicine	Prognostic impact of renal function in precapillary pulmonary hypertension [Pubmed: 24011362]
BMC Nephrology	FGF-23 associated with the progression of coronary artery calcification in hemodialysis patients [Pubmed: 24180481]
Journal of Clinical Densitometry	Lower Fibroblast Growth Factor 23 Levels in Young Adults With Crohn Disease as a Possible Secondary Compensatory Effect on the Disturbance of Bone and Mineral Metabolism [Pubmed: 23623649]
J Intern Med.	Prognostic impact of renal function in precapillary pulmonary hypertension. [Pubmed:24011362]
Journal of Bone and Mineral Research	Adverse effects of osteocytic constitutive activation of ?-catenin on bone strength and bone growth [Pubmed:25639729]
Nefrologia	Fibroblast growth factor is associated to left ventricular mass index, anemia and low values of transferrin saturation El factor de crecimiento fibroblástico está asociado con el índice de masa ventricular izquierda, anemia y niveles bajos de saturación de la transferrina [PubMed: 26394828]
Medicine (Baltimore)	An Attempt to Evaluate Selected Aspects of “Bone–Fat Axis” Function in Healthy Individuals and Patients With Pancreatic Cancer [PubMed: 26266370]
Ann Biol Clin (Paris)	Les biomarqueurs des calcifications vasculaires: quelles limites analytiques pour leur transfert de la recherche bioclinique à la pratique? [PubMed: 26069069]
Scandinavian Journal of Gastroenterology	High-dose fast infusion of parenteral iron isomaltoside is efficacious in inflammatory bowel disease patients with iron-deficiency anaemia without profound changes in phosphate or fibroblast growth factor 23 [Pubmed:27326766]
PLOS?ONE	Prostaglandin-E2?Mediated?Increase?in?Calcium?and?Phosphate?Excretion?in a?Mouse?Model?ofDistal?Nephron?Salt?Wasting. [pubmed:27442254]
Journal of Laboratory Diagnostics	Evaluation of concentration fibroblast growth factor FGF-23 in hemodialysed patients and after kidney transplantation [publication:312592751]
Journal of Integrative Nephrology & Andrology	Associations between serum fibroblast growth factor 23 level and intradialytic hypotension in hemodialysis patients [issn:2394-2916]
Journal of Renal Nutrition	ADAM17, a New Player in the Pathogenesis of Chronic Kidney Disease-Mineral and Bone Disorder. [pubmed:29056164]
Experimental Biology and Medicine(Maywood)	Effect of cross-linked chitosan iron (III) on vascular calcification in uremic rats [Pubmed:29763365]
Psychiatry Research	Cerebrospinal fluid FGF23 levels correlate with a measure of impulsivity [Pubmed:29677623]
BMC?Pediatrics	Serum and urine FGF23 and IGFBP-7 for the prediction of acute kidney injury in critically ill children [Pubmed:29907141]
Medical Science Monitor	Effect of Salt Intervention on Serum Levels of Fibroblast Growth Factor 23 (FGF23) in Chinese Adults: An Intervention Study [Pubmed:29608553]
International Journal of Chronic Obstructive Pulmonary Disease	Disconnection of pulmonary and systemic arterial stiffness in COPD [Pubmed:29881265]
Saudi?journal of?kidney?diseases and transplantation	Prevalence of cardiac arrhythmia and risk factors in chronic kidney disease patients [Pubmed:29970732]
Nephrology Dialysis?Transplantation	High-serum phosphate and parathyroid hormone distinctly regulate bone loss and vascular calcification in experimental chronic kidney disease [Pubmed: 30189026]
BioFactors?	Alteration in serum concentrations of FGF19, FGF21, and FGF23 in patients with urothelial carcinoma [Pubmed: 30334297]
Biological?Trace?Element?Research	Altered Mineral Metabolism and Disequilibrium Between Calcification Promoters and Inhibitors in Chronic Hemodialysis Patients [Pubmed: 30847765]
Clin Implant Dent Relat Res.	Evaluation of FGF‐23 and 25(OH)D3 levels in peri‐implant sulcus fluid in peri‐implant health and diseases [Pubmed: 31407857]
JACC-Cardiovascular Imaging	PREVALANCE AND PROGRESSION OF CARDIOVASCULAR CALCIFICATIONS IN HAEMODIALYSIS PATIENTS [Pubmed: 28797410]
Saudi J Kidney Dis Transpl	Serum fibroblast growth factor 23 levels do not correlate with carotid intima-media thickness in patients with chronic kidney disease [Pubmed: 31696838]
Biomedicine & Pharmacotherapy	MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7 [Pubmed: 31918268]
	Is Serum FGF-23 Associated with Subclinic Atherosclerosis in Patients with AA Amyloidosis? []
	THE RELATIONSHIP BETWEEN ARTERIAL STIFNESS AND 25-(OH) VITAMIN D, FGF 23 IN MAINTENANCE HEMODIALYSIS PATIENTS []
	THE RELATIONSHIP BETWEEN ARTERIAL STIFFNESS AND 25-(OH) VITAMIN D, FGF 23 IN MAINTENANCE HEMODIALYSIS PATIENTS KRON?K ?- []
Calcif Tissue Int	The Measurement and Interpretation of Fibroblast Growth Factor 23 (FGF23) Concentrations [Pubmed:35665817]
European Journal of Medical Genetics	Genetic and clinical profile of patients with hypophosphatemic rickets [Pubmed:35738466]
African Health Sciences	Fibroblast Growth Factor 23 (FGF 23) and intact parathyroid hormone (iPTH) as markers of mineral bone disease among Nigerians with non-diabetic kidney disease []

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