生長(zhǎng)分化因子11(GDF11)重組蛋白
Recombinant Growth Differentiation Factor 11 (GDF11)
BMP11; Bone morphogenetic protein 11
- 編號(hào)RPC113Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位分泌
- 預(yù)測(cè)分子量30.8kDa
- 實(shí)際分子量31kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
- 片段與標(biāo)簽Cys159~Pro395 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 90%
- 等電點(diǎn)9.6
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載 英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure . Gene Sequencing (extract)
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SDS-PAGE圖
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通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPC113Ra01 | 生長(zhǎng)分化因子11(GDF11)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC113Ra01 | 生長(zhǎng)分化因子11(GDF11)多克隆抗體 | WB; IHC; ICC; IP. |
| MAC113Ra21 | 生長(zhǎng)分化因子11(GDF11)單克隆抗體 | WB; IHC; ICC; IP. |
| SEC113Ra | 生長(zhǎng)分化因子11(GDF11)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCC113Ra | 生長(zhǎng)分化因子11(GDF11)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMC113Ra | 生長(zhǎng)分化因子11(GDF11)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Oncotarget | Splenocytes derived from young WT mice prevent AD progression in APPswe/PSENldE9 transgenic mice [PubMed: 26317549] |
| Endocrinology | TGFβ Superfamily Members Mediate Androgen Deprivation Therapy-Induced Obese Frailty in Male Mice [pubmed:27611336] |
| International Journal of Clinical and Experimental Pathology | GDF11 is increased in patients with myelodysplastic syndrome [files:ijcep0024948.pdf] |
| European?Review for?Medical?and Pharmacological?Sciences | GDF11 does not improve the palmitate induced insulin resistance in C2C12. [pubmed:28485800] |
| CyberLeninka | РОЛЬ ДИФФЕРЕНЦИРОВОЧНОГО ФАКТОРА РОСТА 11 (GDF11) В РЕГУЛЯЦИИ ЛИПИДНОГО ОБМЕНА И КАРДИОГЕМОДИНАМИЧЕСКИХ ФУНКЦИЙ?… [Cyberleninka:Source] |
| Hematology | GDF11 is increased in patients with aplastic anemia [Pubmed: 30727851] |
| J Cell Mol Me | GDF11 prevents the formation of thoracic aortic dissection in mice: Promotion of contractile transition of aortic SMCs [33764670] |
| Arch Gynecol Obstet | The relationship between transforming growth factor β superfamily members (GDF11 and BMP4) and lumbar spine bone mineral density in postmenopausal Chinese?… [34417839] |
| Oxidative Medicine and Cellular Longevity | Low-Intensity Exercise Routine for a Long Period of Time Prevents Osteosarcopenic Obesity in Sedentary Old Female Rats, by Decreasing Inflammation and?… [34336096] |
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