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神經(jīng)調(diào)節(jié)素1(NRG1)單克隆抗體

Monoclonal Antibody to Neuregulin 1 (NRG1)

ARIA; GGF; HGL; HRG; HRGA; NDF; SMDF; Acetylcholine receptor-inducing activity; Glial growth factor; Heregulin; Neu differentiation factor; Sensory and motor neuron-derived factor

編號MAB866Hu21
物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 所有
- 人
- 小鼠
- 大鼠
- 豚鼠
- 家兔
- 獼猴
- 山羊
- 綿羊
- 馬
- 牛
- 豬
- 雞
- 狗
- 其他物種
- 多物種
- 泛物種
來源單抗制備
宿主小鼠
效價(克隆號)C4
Ig亞型 IgG1 Kappa
純化方式蛋白A + 蛋白G親和純化
標記物無標記物
免疫原 RPB866Hu01-神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白
緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
性狀液體
濃度1mg/mL
且適物種Rattus norvegicus (Rat，大鼠)
應用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術，請參見流式抗體。
下載英文說明書中文說明書
規(guī)格 20μl100μl 200μl 1ml 10ml
價格 ¥ 648 1512 ¥ 1512 ¥ 2160 ¥ 5400 ¥ 21600
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)

IHC圖

Western Blot; Sample: Lane1: Rat Plasma; Lane2: U2OS cell lysate Primary Ab: 5μg/ml Mouse Anti-Human NRG1 Antibody Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)

通過ISO 9001、ISO 13485質(zhì)量體系認證

特異性

該抗體是針對NRG1的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別NRG1。

用法

Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。

贈品

增值服務

抗體標記定制服務
 Protein-A/G純化柱
 細胞和組織染色液
 抗體陽性對照品
 組織/切片定制服務
 磷酸化抗體定制服務
 免疫印跡(WB)實驗服務
 免疫組織化學(IHC)實驗服務
 免疫細胞化學(ICC)實驗服務
 流式細胞術(FCM)實驗服務
 免疫沉淀(IP)實驗服務
 免疫熒光(IF)實驗服務
 緩沖液
 DAB顯色試劑盒
 SABC試劑盒
 長臂生物素標記試劑盒
 實時熒光定量PCR實驗服務

相關產(chǎn)品

編號	適用物種：Homo sapiens (Human，人)	應用(僅供研究使用，不用于臨床診斷！)
APB866Hu01	神經(jīng)調(diào)節(jié)素1(NRG1)活性蛋白	Cell?culture;?Activity?Assays.
RPB866Hu01	神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
PAB866Hu01	神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體	WB; IHC; ICC; IP.
LAB866Hu71	神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體(生物素標記)	WB; IHC; ICC.
MAB866Hu25	神經(jīng)調(diào)節(jié)素1(NRG1)單克隆抗體	WB
MAB866Hu27	神經(jīng)調(diào)節(jié)素1(NRG1)單克隆抗體	WB; IHC; ICC; IP.
MAB866Hu22	神經(jīng)調(diào)節(jié)素1(NRG1)單克隆抗體	WB
MAB866Hu21	神經(jīng)調(diào)節(jié)素1(NRG1)單克隆抗體	WB; IHC; ICC; IP.
MAB866Hu23	神經(jīng)調(diào)節(jié)素1(NRG1)單克隆抗體	WB; IHC; ICC; IP.
MAB866Hu24	神經(jīng)調(diào)節(jié)素1(NRG1)單克隆抗體	WB; IHC; ICC; IP.
SEB866Hu	神經(jīng)調(diào)節(jié)素1(NRG1)檢測試劑盒(酶聯(lián)免疫吸附試驗法)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMB866Hu	神經(jīng)調(diào)節(jié)素1(NRG1)等多因子檢測試劑盒(流式熒光發(fā)光法)	FLIA Kit for Antigen Detection.
KSB866Hu01	神經(jīng)調(diào)節(jié)素1(NRG1)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法)	Main materials for "Do It(ELISA Kit) Yourself"

參考文獻

雜志	參考文獻
Neuroscience Letter	Therapeutic effect of co-transplantation of neuregulin 1-transfected-Schwann cells and bone marrow stromal cells on spinal cord hemisection syndrom [Cyagen: source]
PLoS One.	ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis [PubMed: PMC3519469]
The Journal of Clinical Investigation	Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration [PubMed: PMC3428100]
Physiol Behav	Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress [PubMed: 26626816]
J Toxicol Sci.?	Effects of prolonged antipsychotic administration on neureCavia (Guinea pig )lin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect. [Pubmed:26961615]
journal of cellular and molecular medicine	Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway. [pubmed:28271613]
Transl Psychiatry.	Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation. [pubmed:28267150]
Human?Molecular?Genetics	A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas [Pubmed: 30335132]
Aging (Albany NY)	Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin [Pubmed: 32920546]

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