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表皮調(diào)節(jié)素(EREG)多克隆抗體

Polyclonal Antibody to Epiregulin (EREG)

EPR; ER; Proepiregulin

  • 表皮調(diào)節(jié)素(EREG)多克隆抗體 產(chǎn)品包裝(模擬)
  • 表皮調(diào)節(jié)素(EREG)多克隆抗體 產(chǎn)品包裝(模擬)
  • Certificate 通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對EREG的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別EREG。

用法

Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。

贈品

相關(guān)產(chǎn)品

編號 適用物種：Mus musculus (Mouse，小鼠) 應(yīng)用(僅供研究使用，不用于臨床診斷！)
RPB945Mu01 表皮調(diào)節(jié)素(EREG)重組蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
RPB945Mu02 表皮調(diào)節(jié)素(EREG)重組蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
PAB945Mu01 表皮調(diào)節(jié)素(EREG)多克隆抗體 WB; IHC; ICC; IP.
PAB945Mu02 表皮調(diào)節(jié)素(EREG)多克隆抗體 WB; IHC; ICC; IP.
SEB945Mu 表皮調(diào)節(jié)素(EREG)檢測試劑盒(酶聯(lián)免疫吸附試驗法) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB945Mu 表皮調(diào)節(jié)素(EREG)檢測試劑盒(化學(xué)發(fā)光免疫分析法) Chemiluminescent immunoassay for Antigen Detection.
LMB945Mu 表皮調(diào)節(jié)素(EREG)等多因子檢測試劑盒(流式熒光發(fā)光法) FLIA Kit for Antigen Detection.

參考文獻(xiàn)

雜志 參考文獻(xiàn)
British Journal of Cancer Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells [Nature: 2012103]
J Pharmacol Exp Ther. Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis. [Pubmed: 24309559]
Molecular Carcinogenesis The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines [Pubmed:23625689]
Am J Physiol Gastrointest Liver Physiol. Epiregulin promotes the emergence and proliferation of adult liver progenitor cells. [Pubmed:24812054]
European Review for Medical and Pharmacological Sciences Epiregulin-loaded PLGA nanoparticles increase human keratinocytes proliferation: preliminary data [pubmed:27383296]
Oncotarget Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation [PMC5593575]
American journal of respiratory cell and molecular biology Potential Involvement of the Epidermal Growth Factor Receptor Ligand Epiregulin and Matrix Metalloproteinase-1 in Pathogenesis of Chronic Rhinosinusitis [pubmed:28398769]
International?Journal?of?Cancer Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer [Pubmed: 30252132]
Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways [Doi: 10.1097/PR9.0000000000000718]
Cell proliferation Epiregulin enhances odontoblastic differentiation of dental pulp stem cells via activating MAPK signalling pathway [Pubmed: 31454111]
International Journal of Molecular Sciences Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts [Pubmed: 31771279]
Neoplasia Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine [Pubmed: 33212364]
Reprod Sci Compromised Cumulus-Oocyte Complex Matrix Organization and Expansion in Women with PCOS [34748173]
Tissue and Cell MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis [34715618]
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