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M2-型丙酮酸激酶(PKM2)重組蛋白

Recombinant Pyruvate kinase isozymes M2 (PKM2)

M2PK; PKM; M2-PK; PKM1; CTHBP; OIP3; PK3; PKM; TCB; THBP1; Pyruvate kinase muscle isozyme; Thyroid hormone-binding protein 1; Cytosolic thyroid hormone-binding protein; Pyruvate Kinase, Muscle

編號(hào)RPA588Hu02
物種Homo sapiens (Human，人) 相同的名稱(chēng)，不同的物種。
- 所有
- 人
- 小鼠
- 大鼠
- 豚鼠
- 家兔
- 獼猴
- 山羊
- 綿羊
- 馬
- 牛
- 豬
- 雞
- 狗
- 其他物種
- 多物種
- 泛物種
來(lái)源原核表達(dá)
宿主E.coli
內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
亞細(xì)胞定位細(xì)胞核, 細(xì)胞質(zhì)
預(yù)測(cè)分子量49.3kDa
實(shí)際分子量50kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
片段與標(biāo)簽Arg294~Phe470 with N-terminal His and GST Tag
緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
性狀凍干粉
純度> 97%
等電點(diǎn)8.3
應(yīng)用 Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。
下載英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)

Figure . Gene Sequencing (extract)

SDS-PAGE圖

通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

序列

用法

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

儲(chǔ)存

避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。

贈(zèng)品

聚丙烯酰胺凝膠電泳(PAGE)實(shí)驗(yàn)服務(wù)

增值服務(wù)

去內(nèi)毒素試劑盒
 BCA蛋白定量檢測(cè)試劑盒
 蛋白標(biāo)記定制服務(wù)
蛋白分子量MARKER
重組蛋白定制服務(wù)
單克隆抗體定制服務(wù)
多克隆抗體定制服務(wù)
蛋白活性測(cè)定實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
緩沖液
 內(nèi)毒素去除試劑盒Ⅱ
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
棘突蛋白受體結(jié)合結(jié)構(gòu)域
 蛋白G
蛋白 A

相關(guān)產(chǎn)品

編號(hào)	適用物種：Homo sapiens (Human，人)	應(yīng)用(僅供研究使用，不用于臨床診斷！)
RPA588Hu01	M2-型丙酮酸激酶(PKM2)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA588Hu02	M2-型丙酮酸激酶(PKM2)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA588Hu03	M2-型丙酮酸激酶(PKM2)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
APA588Hu02	M2-型丙酮酸激酶(PKM2)活性蛋白	Cell?culture;?Activity?Assays.
PAA588Hu02	M2-型丙酮酸激酶(PKM2)多克隆抗體	WB; IHC; IF;FCM
PAA588Hu03	M2-型丙酮酸激酶(PKM2)多克隆抗體	WB; IHC; ICC; IP.
PAA588Hu01	M2-型丙酮酸激酶(PKM2)多克隆抗體	WB,IHC,ICC/IF; FCM
FAA588Hu01	抗M2-型丙酮酸激酶(PKM2)多克隆抗體	Flow cytometry.
FAA588Hu03	抗M2-型丙酮酸激酶(PKM2)多克隆抗體	Flow cytometry.
MAA588Hu24	M2-型丙酮酸激酶(PKM2)單克隆抗體	WB; IHC; ICC; IP.
MAA588Hu22	M2-型丙酮酸激酶(PKM2)單克隆抗體	WB; IHC; ICC; IP.
MAA588Hu23	M2-型丙酮酸激酶(PKM2)單克隆抗體	WB; IHC; ICC; IP.
MAA588Hu21	M2-型丙酮酸激酶(PKM2)單克隆抗體	WB; IHC; ICC; IP.
SEA588Hu	M2-型丙酮酸激酶(PKM2)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMA588Hu	M2-型丙酮酸激酶(PKM2)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)	FLIA Kit for Antigen Detection.

參考文獻(xiàn)

雜志	參考文獻(xiàn)
Cancer Research	Antigen Presentation by Dendritic Cells in Tumors Is Disrupted by Altered Metabolism that Involves Pyruvate Kinase M2 and Its Interaction with SOCS3 [AACR: 70189]
Molecular BioSystems	Abnormal levels of heterogeneous nuclear ribonucleoprotein A2B1 (hnRNPA2B1) in tumour tissue and blood samples from patients diagnosed with lung cancer [Pubmed:25483567]
Tumour Biol	M2 isoform of pyruvate kinase (PKM2) is upregulated in Kazakh’s ESCC and promotes proliferation and migration of ESCC cells [PubMed: 26404132]
Oncotarget	Identification of a serum biomarker panel for the differential diagnosis of cholangiocarcinoma and primary sclerosing cholangitis [Pubmed:29707118]
Journal of?Neurotrauma	Acteoside improves muscle atrophy and motor function by inducing new myokine secretion in chronic spinal cord injury [Pubmed: 30318996]
Cell Reports	Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway [Pubmed: 32049010]
	Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma (ESCC) []
Cancer Cell International	Bufalin Induced Mitochondrial Dysfunction Promotes Apoptosis of Glioma Cells by Regulating Annexin A2 and DRP1 Proteins []
Cancer Cell Int	Bufalin induces mitochondrial dysfunction and promotes apoptosis of glioma cells by regulating Annexin A2 and DRP1 protein expression [34376212]
Life (Basel)	Putative Association between Low Baseline Gene Expression in the Peripheral Blood and Clinical Remission in Rheumatoid Arthritis Patients Treated with Tofacitinib [34947916]

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