Jagged 1蛋白(JAG1)重組蛋白
Recombinant Jagged 1 (JAG1)
CD339; AGS; AHD; AWS; HJ1; JAGL1; Alagille Syndrome; Jagged 1 Protein
- 編號(hào)RPB807Ra01
- 物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位細(xì)胞膜
- 預(yù)測(cè)分子量31.9kDa
- 實(shí)際分子量32kDa(差異分析請(qǐng)參閱說明書)
- 片段與標(biāo)簽Ser826~Cys1084 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 97%
- 等電點(diǎn)6.1
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應(yīng)用
Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見活性蛋白。 - 下載 英文說明書 中文說明書
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價(jià)格 ¥ 996 ¥ 2490 ¥ 4980 ¥ 14940 ¥ 37350
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPB807Ra01 | Jagged 1蛋白(JAG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| 13 | Cross-talk between the Toll-like receptor 4 and Notch1 pathways augments the inflammatory response in the interstitial cells of stenotic human aortic valves [PubMed: PMC3506187] |
| Eur J Obstet Gynecol Reprod Biol. | Profiling of selected angiogenesis-related genes in proliferative eutopic endometrium of women with endometriosis [Pubmed: 24188612] |
| PLoS One. | Augmented Osteogenic Responses in Human Aortic Valve Cells Exposed to oxLDL and TLR4 Agonist: A Mechanistic Role of Notch1 and NF-κB Interaction [Pubmed:Pmc4014478] |
| Biochim Biophys Acta.? | Ligation of ICAM-1 on human aortic valve interstitial cells induces the osteogenic response: A critical role of the Notch1-NF-κB pathway in BMP-2 expression [Pubmed:25101972] |
| international journal of oral-medical sciences | Jagged1 Stimulates Bone Resorption during Orthodontic Tooth Movement [Dn: Jlc] |
| Oncology letters | MicroRNA?26b acts as an antioncogene and prognostic factor in cervical cancer [] |
| Journal of Biological Chemistry | Growth hormone induces Notch1 signaling in podocytes and contributes to proteinuria in diabetic nephropathy [Pubmed: 31511328] |
| Cell Death & Disease | Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria [33795655] |
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