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基質(zhì)金屬蛋白酶3(MMP3)重組蛋白

Recombinant Matrix Metalloproteinase 3 (MMP3)

SL1; STMY; STMY1; STR1; Progelatinase; Stromelysin 1; Transin-1

編號RPA101Hu04
物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 所有
- 人
- 小鼠
- 大鼠
- 豚鼠
- 家兔
- 獼猴
- 山羊
- 綿羊
- 馬
- 牛
- 豬
- 雞
- 狗
- 其他物種
- 多物種
- 泛物種
來源原核表達(dá)
宿主E.coli
內(nèi)毒素水平<1.0EU/µg(LAL法測定)
亞細(xì)胞定位分泌, 細(xì)胞外基質(zhì)
預(yù)測分子量55.9kDa
實(shí)際分子量56kDa(差異分析請參閱說明書)
片段與標(biāo)簽Tyr18~Cys477 with N-terminal His Tag
緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
性狀凍干粉
純度> 90%
等電點(diǎn)5.9
應(yīng)用 Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。
下載英文說明書中文說明書
規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)

Figure . Gene Sequencing (extract)

Figure. SDS-PAGE

通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

序列

用法

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

儲存

避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。

贈(zèng)品

聚丙烯酰胺凝膠電泳(PAGE)實(shí)驗(yàn)服務(wù)

增值服務(wù)

去內(nèi)毒素試劑盒
 BCA蛋白定量檢測試劑盒
 蛋白標(biāo)記定制服務(wù)
蛋白分子量MARKER
重組蛋白定制服務(wù)
單克隆抗體定制服務(wù)
多克隆抗體定制服務(wù)
蛋白活性測定實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
緩沖液
 內(nèi)毒素去除試劑盒Ⅱ
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
棘突蛋白受體結(jié)合結(jié)構(gòu)域
 蛋白G
蛋白 A

相關(guān)產(chǎn)品

編號	適用物種：Homo sapiens (Human，人)	應(yīng)用(僅供研究使用，不用于臨床診斷！)
EPA101Hu62	基質(zhì)金屬蛋白酶3(MMP3)真核蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
APA101Hu62	基質(zhì)金屬蛋白酶3(MMP3)活性蛋白	Cell?culture;?Activity?Assays.
RPA101Hu01	基質(zhì)金屬蛋白酶3(MMP3)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA101Hu02	基質(zhì)金屬蛋白酶3(MMP3)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA101Hu04	基質(zhì)金屬蛋白酶3(MMP3)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA101Hu03	基質(zhì)金屬蛋白酶3(MMP3)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
APA101Hu61	基質(zhì)金屬蛋白酶3(MMP3)活性蛋白	Cell?culture;?Activity?Assays.
RPA101Hu05	基質(zhì)金屬蛋白酶3(MMP3)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
PAA101Hu02	基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體	WB; IHC; ICC; IP.
PAA101Hu01	基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體	WB; IHC; ICC; IP.
PAA101Hu05	基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體	WB; IHC; ICC; IP.
PAA101Hu03	基質(zhì)金屬蛋白酶3(MMP3)多克隆抗體	WB; IHC; ICC; IP.
MAA101Hu22	基質(zhì)金屬蛋白酶3(MMP3)單克隆抗體	WB; IHC; ICC; IP.
MAA101Hu23	基質(zhì)金屬蛋白酶3(MMP3)單克隆抗體	WB; IHC; ICC; IP.
MAA101Hu21	基質(zhì)金屬蛋白酶3(MMP3)單克隆抗體	WB; IHC; ICC; IP.
LAA101Hu72	基質(zhì)金屬蛋白酶3(MMP3)單克隆抗體(生物素標(biāo)記)	WB; IHC; ICC.
SEA101Hu	基質(zhì)金屬蛋白酶3(MMP3)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)	Enzyme-linked immunosorbent assay for Antigen Detection.
SCA101Hu	基質(zhì)金屬蛋白酶3(MMP3)檢測試劑盒(化學(xué)發(fā)光免疫分析法)	Chemiluminescent immunoassay for Antigen Detection.
LMA101Hu	基質(zhì)金屬蛋白酶3(MMP3)等多因子檢測試劑盒(流式熒光發(fā)光法)	FLIA Kit for Antigen Detection.
PSA101Hu01	基質(zhì)金屬蛋白酶3(MMP3)抗體對	ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays.
KSA101Hu01	基質(zhì)金屬蛋白酶3(MMP3)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗(yàn)法)	Main materials for "Do It (ELISA Kit) Yourself".

參考文獻(xiàn)

雜志	參考文獻(xiàn)
Journal of Bone and Joint Surgery	Experimental osteoarthritis induced by surgical realignment of the patella in BALB/c mice [PubMed: 21119180]
Infection and Immunity	Bovine Respiratory Syncytial Virus and Histophilus somni Interaction at the Alveolar Barrier [Pubmed: 23649093]
PLoS ONE	A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches [Plosone: Source]
China Pharmacy	Influence of Tongfengtai Granules on Inflammatory Factor in Acute Gouty Arthritis Model Rats [Source]
Thromb Haemost.	Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke [Pubmed:24671655]
Connective Tissue Research	Metabolic and cytoprotective effects of in vivo peri-patellar hyaluronic acid injections in cultured tenocytes [Pubmed:25333747]
physiological research	The skin remodeling in type 1 diabetes and insulin resistance animal models [PubMed: 26047379]
Physiol Res	The skin remodeling in type 1 diabetes and insulin resistance animal models. [PubMed: 26047379]
Cellular & Molecular Immunology	Effect of ebosin on modulating interleukin-2&bgr;-induced inflammatory responses in rat fibroblast-like synoviocytes [PubMed: 25938977]
Biol Res	The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritis [PubMed: 26578310]
J Orthop Res.	Tetrandrine suppresses articular inflammatory response by inhibiting pro-inflammatory factors via NF-κB inactivation. [Pubmed:26748661]
Cellular?& Molecular Immunology	Effect of ebosin on modulating interleukin-1β-induced inflammatory responses in rat fibroblast-like synoviocytes [pubmed:25938977]
Journal of Orthopaedic?Research	Tetrandrine suppresses articular inflammatory response by inhibiting pro‐inflammatory factors via NF‐κB inactivation [pubmed:26748661]
Mediators?of?Inflammation	Interleukin-29?Enhances?Synovial?Inflammation?and?Cartilage?Degradation?in?Osteoarthritis. [pubmed:27433031]
Molecular Medicine Reports	Icariin inhibits MMP?1, MMP?3 and MMP?13 expression through MAPK pathways in IL?1β?stimulated SW1353 chondrosarcoma cells [pubmed:28447732]
der Christian-Albrechts-Universit?t zu Kiel	Wirkung schonender Laserverfahren auf den Komplexaus retinalem Pigmentepithel, Bruch′scher Membranund Choroidea - m?gliche Therapieoption der frühen altersabh?ngigen Makuladegeneration [1133074014:34]
REDVET - Revista electrónica de Veterinaria	Measurement of Metalloproteinase-3 levels in synovial fluid from horses as biomarker of joint disease [E-ISSN: 1695-7504]
REDVET - Revista electrónica de Veterinaria	Measurement of Metalloproteinase-3 levels in synovial fluid from horses as biomarker of joint disease - Medición de los niveles de Metaloproteinasa-3 en liquido sinovial comobiomarcador de enfermedad articular [ISSN 1695-7504]
Molecular Pharmacology	Dexamethasone Down-regulates Endothelin Receptors and Reduces Endothelin-induced Production of Matrix Metalloproteinases in Cultured Rat Astrocytes [10.1124/mol.116.107300]
Theranostics	Targeting intracellular MMPs efficiently inhibits tumor metastasis and angiogenesis [Pubmed:29774078]
Chinese Journal of Integrative Medicine	Electroacupuncture Delays Cartilage Degeneration by Modulating Nuclear Factor-κB Signaling Pathway [Pubmed: 30656598]
	Effects of a hyperimmunized egg product on voluntary physical activity levels, serum inflammatory markers, and owner perception of joint pain of dogs with?… []
PLoS One	Co-culture of osteochondral explants and synovial membrane as in vitro model for osteoarthritis [Pubmed: 30939166]
ACS Biomaterials Science & Engineering	Fluorogenic Probe for Detecting Active Matrix Metalloproteinase-3 (MMP-3) in Plasma and Peripheral Blood Neutrophils to Indicate the Severity of Rheumatoid?… []
World Journal of Pediatrics	Regulation of JAK/STAT signal pathway by miR-21 in the pathogenesis of juvenile idiopathic arthritis [Pubmed: 31641939]
International Journal of Molecular Sciences	Matrix Metalloproteinase-3 is Key Effector of TNF-α-Induced Collagen Degradation in Skin [Pubmed: 31652545]
JOURNAL OF CELLULAR BIOCHEMISTRY	Teneligliptin inhibits IL‐1β‐induced degradation of extracellular matrix in human chondrocytes [Pubmed: 32162384]
Bone Research	Effects of tetrahedral framework nucleic acid/wogonin complexes on osteoarthritis [Pubmed: 32047705]
Scientific Reports	Matrix metallopeptidase expression and modulation by transforming growth factor-β1 in equine endometrosis [Pubmed: 31980722]
Alexandria Journal for Veterinary Sciences	The Clinicopathological Picture of Some Postpartum Disorders in Barki Ewes. []
	Identification of Polyphenolic Compounds and Hepatoprotective Activity of Artichoke (Cynara Scolymus L.) Edible Part Extracts in Rats []
Food Funct	Undenatured type II collagen prevents and treats the osteoarthritis and motor function degradation in T2DM patients and db/db mice [33890588]
journal biomedicine translational research	Peanut (Arachis hypogaea) Shells Extract and Apis dorsata Honey Reduce Matrix Metalloproteinase-3 in Monosodium Iodoacetate-Induced Osteoarthritic??- []
JOURNAL OF ANIMAL SCIENCE	Physical Activity Patterns of Free Living Dogs Diagnosed with Osteoarthritis [34216471]
Osteoarthritis Cartilage	A systematic review on the potential value of synovial fluid biomarkers to predict clinical outcomes in cartilage repair treatments [Pubmed:35618204]
Phytomedicine	Transcriptomic profiling revealed the role of apigenin-4′-O-α-L-rhamnoside in inhibiting the activation of rheumatoid arthritis fibroblast-like synoviocytes via MAPK?… [Pubmed:35660352]
Journal of Immunology Research	Ebosin Attenuates the Inflammatory Responses Induced by TNF-α through Inhibiting NF-κB and MAPK Pathways in Rat Fibroblast-Like Synoviocytes [Pubmed:35340587]

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