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粘蛋白5B(MUC5B)重組蛋白

Recombinant Mucin 5 Subtype B (MUC5B)

MUC5-B; MUC9; MG1; Oligomeric Mucus/Gel-Forming; Mucin 5,Subtype B,Tracheobronchial; Cervical mucin; High molecular weight salivary mucin MG1; Sublingual gland mucin

編號RPA684Hu02
物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 所有
- 人
- 小鼠
- 大鼠
- 豚鼠
- 家兔
- 獼猴
- 山羊
- 綿羊
- 馬
- 牛
- 豬
- 雞
- 狗
- 其他物種
- 多物種
- 泛物種
來源原核表達(dá)
宿主E.coli
內(nèi)毒素水平<1.0EU/µg(LAL法測定)
亞細(xì)胞定位分泌
預(yù)測分子量15.7kDa
實(shí)際分子量16kDa(差異分析請參閱說明書)
片段與標(biāo)簽Cys5653~Val5762 with N-terminal His Tag
緩沖液成份100mMNaHCO3, 500mMNaCl, pH8.3, containing 0.01% SKL, 5% Trehalose.
性狀凍干粉
純度> 90%
等電點(diǎn)5.1
應(yīng)用 Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。
下載英文說明書中文說明書
規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)

Figure. Gene Sequencing (Extract)

Figure. SDS-PAGE

通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

序列

用法

Reconstitute in ddH₂O to a concentration of 0.1-1.0 mg/mL. Do not vortex.

儲存

避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。

贈品

聚丙烯酰胺凝膠電泳(PAGE)實(shí)驗(yàn)服務(wù)

增值服務(wù)

去內(nèi)毒素試劑盒
 BCA蛋白定量檢測試劑盒
 蛋白標(biāo)記定制服務(wù)
蛋白分子量MARKER
重組蛋白定制服務(wù)
單克隆抗體定制服務(wù)
多克隆抗體定制服務(wù)
蛋白活性測定實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
緩沖液
 內(nèi)毒素去除試劑盒Ⅱ
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
棘突蛋白受體結(jié)合結(jié)構(gòu)域
 蛋白G
蛋白 A

相關(guān)產(chǎn)品

編號	適用物種：Homo sapiens (Human，人)	應(yīng)用(僅供研究使用，不用于臨床診斷！)
RPA684Hu02	粘蛋白5B(MUC5B)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA684Hu01	粘蛋白5B(MUC5B)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
CPA684Hu21	粘蛋白5B(MUC5B)卵白蛋白偶聯(lián)物	Immunogen; SDS-PAGE; WB.
PAA684Hu01	粘蛋白5B(MUC5B)多克隆抗體	WB; IHC; ICC; IP.
PAA684Hu02	粘蛋白5B(MUC5B)多克隆抗體	WB; IHC; ICC; IP.
LAA684Hu81	粘蛋白5B(MUC5B)多克隆抗體(異硫氰酸熒光素標(biāo)記)	WB; IHC; ICC; IF.
LAA684Hu71	粘蛋白5B(MUC5B)多克隆抗體(生物素標(biāo)記)	WB; IHC; ICC.
MAA684Hu27	粘蛋白5B(MUC5B)單克隆抗體	WB; IHC; ICC; IP.
MAA684Hu28	粘蛋白5B(MUC5B)單克隆抗體	IHC
MAA684Hu21	粘蛋白5B(MUC5B)單克隆抗體	WB; IHC; ICC; IP.
MAA684Hu22	粘蛋白5B(MUC5B)單克隆抗體	WB
MAA684Hu23	粘蛋白5B(MUC5B)單克隆抗體	WB; IHC; ICC; IP.
MAA684Hu24	粘蛋白5B(MUC5B)單克隆抗體	WB; IHC; ICC; IP.
MAA684Hu25	粘蛋白5B(MUC5B)單克隆抗體	WB; IHC; ICC; IP.
MAA684Hu29	粘蛋白5B(MUC5B)單克隆抗體	WB; IHC; ICC; IP.
SEA684Hu	粘蛋白5B(MUC5B)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)	Enzyme-linked immunosorbent assay for Antigen Detection.
SCA684Hu	粘蛋白5B(MUC5B)檢測試劑盒(化學(xué)發(fā)光免疫分析法)	Chemiluminescent immunoassay for Antigen Detection.
LMA684Hu	粘蛋白5B(MUC5B)等多因子檢測試劑盒(流式熒光發(fā)光法)	FLIA Kit for Antigen Detection.

參考文獻(xiàn)

雜志	參考文獻(xiàn)
The Journal of Biological Chemistry	The Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase/Ribosomal S6 Protein Kinase 1 Cascade Phosphorylates cAMP Response Element-binding Protein to Induce MUC5B Gene Expression via D-Prostanoid Receptor Signaling [Jcb: 34199]
The Journal of Biological Chemistry	The ERK MAPK/RSK1 cascade phosphorylates CREB to induce MUC5B gene expression via DP1 receptor signaling [Jcb: 247684]
Respiratory Researh	Pyocyanin-induced mucin production is associated with redox modification of FOXA2 [PubMed: PMC3765780]
Respirology	Secreted mucins and airway bacterial colonization in non-CF bronchiectasis [PubMed: 26172851]
American Thoracic Society International Conference Abstracts	Mucin Secretion In Asthmatics With Osmotic Airway Hyperresponsiveness [doi:10.1164]
Ann Am Thorac Soc	Airway Mucin 2 Is Decreased in Patients with Severe Chronic Obstructive Pulmonary Disease with Bacterial Colonization [doi:10.1513]
	Секреторно-экссудативная реакция слизистой носа на воздействие холодного воздуха у больных бронхиальной астмой [10.20538/1682-0363-2017-2-146-158]
Allergy	Th2 cytokines orchestrate the secretion of MUC 5 AC and MUC 5B in IL‐5 positive chronic rhinosinusitis with nasal polyps [Pubmed:29802623]
European?Journal of Pharmacology?	Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling [Pubmed:29382534]
Japan Society of Immunology & Allergology in Otolaryngology	インフルエンザ菌Phosphorylcholine の表出と中耳ムチンMUC5AC 及びMUC5B 産生への影響 [10.5648:jjiao.36.7]
Journal of Investigative?Medicine	The characteristics and clinical significance of mucin levels in bronchoalveolar lavage fluid of patients with interstitial lung disease [Pubmed: 30573494]
Mucosal Immunology	ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism [Pubmed: 31278375]

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