表皮調(diào)節(jié)素(EREG)多克隆抗體
Polyclonal Antibody to Epiregulin (EREG)
EPR; ER; Proepiregulin
- 編號PAB945Hu01
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標記物無標記物
- 免疫原 RPB945Hu01-表皮調(diào)節(jié)素(EREG)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度0.5mg/ml
- 且適物種Sus scrofa; Porcine (Pig，豬)
- 應用WB
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 598 ¥ 1394 ¥ 1992 ¥ 4980 ¥ 19920
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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IHC圖
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Figure. Western Blot; Sample: Recombinant EREG, Human.
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Western Blot; Sample: Porcine Tongue lysate<br/>Primary Ab: 0.05μg/ml Rabbit Anti-Human EREG Antibody<br/>Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody<br/>(Catalog: SAA544Rb19) Selected
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通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對EREG的兔多克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別EREG。
用法
Western blotting: 0.01-2μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPB945Hu02 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB945Hu04 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB945Hu01 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB945Hu03 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB945Hu02 | 表皮調(diào)節(jié)素(EREG)多克隆抗體 | WB |
| PAB945Hu01 | 表皮調(diào)節(jié)素(EREG)多克隆抗體 | WB |
| PAB945Hu04 | 表皮調(diào)節(jié)素(EREG)多克隆抗體 | WB; IHC; ICC; IP. |
| MAB945Hu22 | 表皮調(diào)節(jié)素(EREG)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB945Hu | 表皮調(diào)節(jié)素(EREG)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB945Hu | 表皮調(diào)節(jié)素(EREG)檢測試劑盒(化學發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMB945Hu | 表皮調(diào)節(jié)素(EREG)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| British Journal of Cancer | Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells [Nature: 2012103] |
| J Pharmacol Exp Ther. | Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis. [Pubmed: 24309559] |
| Molecular Carcinogenesis | The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines [Pubmed:23625689] |
| Am J Physiol Gastrointest Liver Physiol. | Epiregulin promotes the emergence and proliferation of adult liver progenitor cells. [Pubmed:24812054] |
| European Review for Medical and Pharmacological Sciences | Epiregulin-loaded PLGA nanoparticles increase human keratinocytes proliferation: preliminary data [pubmed:27383296] |
| Oncotarget | Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation [PMC5593575] |
| American journal of respiratory cell and molecular biology | Potential Involvement of the Epidermal Growth Factor Receptor Ligand Epiregulin and Matrix Metalloproteinase-1 in Pathogenesis of Chronic Rhinosinusitis [pubmed:28398769] |
| International?Journal?of?Cancer | Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer [Pubmed: 30252132] |
| Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways [Doi: 10.1097/PR9.0000000000000718] | |
| Cell proliferation | Epiregulin enhances odontoblastic differentiation of dental pulp stem cells via activating MAPK signalling pathway [Pubmed: 31454111] |
| International Journal of Molecular Sciences | Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts [Pubmed: 31771279] |
| Neoplasia | Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine [Pubmed: 33212364] |
| Reprod Sci | Compromised Cumulus-Oocyte Complex Matrix Organization and Expansion in Women with PCOS [34748173] |
| Tissue and Cell | MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis [34715618] |
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