表皮調(diào)節(jié)素(EREG)多克隆抗體
Polyclonal Antibody to Epiregulin (EREG)
EPR; ER; Proepiregulin
- 編號PAB945Hu04
- 物種Homo sapiens (Human,人) 相同的名稱,不同的物種。
- 來源多抗制備
- 宿主兔
- 效價(jià)-
- Ig類型 IgG
- 純化方式抗原特異性親和純化
- 標(biāo)記物無標(biāo)記物
- 免疫原 -
- 緩沖液成份磷酸鹽緩沖液(pH7.4,含有0.02% NaN3和50%甘油)
- 性狀液體
- 濃度500μg/mL
- 且適物種-
- 應(yīng)用WB; IHC; ICC; IP.
如果抗體需用于流式細(xì)胞術(shù),請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價(jià)格 ¥ 607 ¥ 1415 ¥ 2022 ¥ 5055 ¥ 20220
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特異性
該抗體是針對EREG的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別EREG。
用法
免疫印跡:0.2-2μg/mL;1:250-2500
免疫組織化學(xué):5-20μg/mL;1:25-100
免疫細(xì)胞化學(xué):5-20μg/mL;1:25-100
最佳稀釋倍數(shù)最終由用戶決定。
儲(chǔ)存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定,具體方法如下:在37°C孵育48小時(shí),沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲(chǔ),損失率低于5%。
贈(zèng)品
增值服務(wù)
抗體標(biāo)記定制服務(wù)
Protein-A/G純化柱
細(xì)胞和組織染色液
抗體陽性對照品
組織/切片定制服務(wù)
磷酸化抗體定制服務(wù)
免疫印跡(WB)實(shí)驗(yàn)服務(wù)
免疫組織化學(xué)(IHC)實(shí)驗(yàn)服務(wù)
免疫細(xì)胞化學(xué)(ICC)實(shí)驗(yàn)服務(wù)
流式細(xì)胞術(shù)(FCM)實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
免疫熒光(IF)實(shí)驗(yàn)服務(wù)
緩沖液
DAB顯色試劑盒
SABC試劑盒
長臂生物素標(biāo)記試劑盒
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
相關(guān)產(chǎn)品
編號 | 適用物種:Homo sapiens (Human,人) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) |
RPB945Hu02 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB945Hu04 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB945Hu01 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB945Hu03 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB945Hu02 | 表皮調(diào)節(jié)素(EREG)多克隆抗體 | WB |
PAB945Hu01 | 表皮調(diào)節(jié)素(EREG)多克隆抗體 | WB |
PAB945Hu04 | 表皮調(diào)節(jié)素(EREG)多克隆抗體 | WB; IHC; ICC; IP. |
MAB945Hu22 | 表皮調(diào)節(jié)素(EREG)單克隆抗體 | WB; IHC; ICC; IP. |
SEB945Hu | 表皮調(diào)節(jié)素(EREG)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCB945Hu | 表皮調(diào)節(jié)素(EREG)檢測試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
LMB945Hu | 表皮調(diào)節(jié)素(EREG)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
雜志 | 參考文獻(xiàn) |
British Journal of Cancer | Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells [Nature: 2012103] |
J Pharmacol Exp Ther. | Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis. [Pubmed: 24309559] |
Molecular Carcinogenesis | The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines [Pubmed:23625689] |
Am J Physiol Gastrointest Liver Physiol. | Epiregulin promotes the emergence and proliferation of adult liver progenitor cells. [Pubmed:24812054] |
European Review for Medical and Pharmacological Sciences | Epiregulin-loaded PLGA nanoparticles increase human keratinocytes proliferation: preliminary data [pubmed:27383296] |
Oncotarget | Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation [PMC5593575] |
American journal of respiratory cell and molecular biology | Potential Involvement of the Epidermal Growth Factor Receptor Ligand Epiregulin and Matrix Metalloproteinase-1 in Pathogenesis of Chronic Rhinosinusitis [pubmed:28398769] |
International?Journal?of?Cancer | Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer [Pubmed: 30252132] |
Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways [Doi: 10.1097/PR9.0000000000000718] | |
Cell proliferation | Epiregulin enhances odontoblastic differentiation of dental pulp stem cells via activating MAPK signalling pathway [Pubmed: 31454111] |
International Journal of Molecular Sciences | Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts [Pubmed: 31771279] |
Neoplasia | Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine [Pubmed: 33212364] |
Reprod Sci | Compromised Cumulus-Oocyte Complex Matrix Organization and Expansion in Women with PCOS [34748173] |
Tissue and Cell | MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis [34715618] |