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表皮生長因子受體(EGFR)重組蛋白

Recombinant Epidermal Growth Factor Receptor (EGFR)

ErbB-1; ErbB1; ER1; ERB-B1; MENA; HER1; Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog,Avian; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

編號RPA757Hu01
物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 所有
- 人
- 小鼠
- 大鼠
- 豚鼠
- 家兔
- 獼猴
- 山羊
- 綿羊
- 馬
- 牛
- 豬
- 雞
- 狗
- 其他物種
- 多物種
- 泛物種
來源原核表達(dá)
宿主E.coli
內(nèi)毒素水平<1.0EU/µg(LAL法測定)
亞細(xì)胞定位細(xì)胞膜, 分泌
預(yù)測分子量37.6kDa
實(shí)際分子量37kDa(差異分析請參閱說明書)
片段與標(biāo)簽Lys713~Asp984 with N-terminal His Tag
緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
性狀凍干粉
純度> 80%
等電點(diǎn)6.7
應(yīng)用 Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。
下載英文說明書中文說明書
規(guī)格 10μg50μg 200μg 1mg 5mg
價格 ¥ 720 1800 ¥ 1800 ¥ 3600 ¥ 10800 ¥ 27000
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)

Figure. Gene Sequencing (Extract)

Figure. SDS-PAGE

通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

序列

用法

Reconstitute in ddH₂O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

儲存

避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。

贈品

聚丙烯酰胺凝膠電泳(PAGE)實(shí)驗(yàn)服務(wù)

增值服務(wù)

去內(nèi)毒素試劑盒
 BCA蛋白定量檢測試劑盒
 蛋白標(biāo)記定制服務(wù)
蛋白分子量MARKER
重組蛋白定制服務(wù)
單克隆抗體定制服務(wù)
多克隆抗體定制服務(wù)
蛋白活性測定實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
緩沖液
 內(nèi)毒素去除試劑盒Ⅱ
實(shí)時熒光定量PCR實(shí)驗(yàn)服務(wù)
棘突蛋白受體結(jié)合結(jié)構(gòu)域
 蛋白G
蛋白 A

相關(guān)產(chǎn)品

編號	適用物種：Homo sapiens (Human，人)	應(yīng)用(僅供研究使用，不用于臨床診斷！)
APA757Hu01	表皮生長因子受體(EGFR)活性蛋白	Cell?culture;?Activity?Assays.
APA757Hu02	表皮生長因子受體(EGFR)活性蛋白	Cell?culture;?Activity?Assays.
APA757Hu62	表皮生長因子受體(EGFR)活性蛋白	Cell?culture;?Activity?Assays.
RPA757Hu01	表皮生長因子受體(EGFR)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
APA757Hu61	表皮生長因子受體(EGFR)活性蛋白	Cell?culture;?Activity?Assays.
EPA757Hu62	表皮生長因子受體(EGFR)真核蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
RPA757Hu02	表皮生長因子受體(EGFR)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
EPA757Hu61	表皮生長因子受體(EGFR)真核蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
PAA757Hu06	表皮生長因子受體(EGFR)多克隆抗體	WB; IHC; ICC; IP.
PAA757Hu02	表皮生長因子受體(EGFR)多克隆抗體	WB; IHC; ICC; IP.
PAA757Hu01	表皮生長因子受體(EGFR)多克隆抗體	WB; IHC; ICC; IP.
FAA757Hu51	抗表皮生長因子受體(EGFR)多克隆抗體(別藻藍(lán)蛋白標(biāo)記)	FCM
MAA757Hu27	表皮生長因子受體(EGFR)單克隆抗體	WB; IHC; ICC; IP.
MAA757Hu29	表皮生長因子受體(EGFR)單克隆抗體	WB; IHC; ICC; IP.
RAA757Hu21	表皮生長因子受體(EGFR)重組抗體	WB; IF; ICC; IHC; IP; FCM.
MAA757Hu21	表皮生長因子受體(EGFR)單克隆抗體	WB; IHC; ICC; IP.
MAA757Hu23	表皮生長因子受體(EGFR)單克隆抗體	WB; IHC; ICC; IP.
MAA757Hu24	表皮生長因子受體(EGFR)單克隆抗體	WB; IHC; ICC; IP.
MAA757Hu25	表皮生長因子受體(EGFR)單克隆抗體	WB; IHC; ICC; IP.
MAA757Hu22	表皮生長因子受體(EGFR)單克隆抗體	WB; IHC
SEA757Hu	表皮生長因子受體(EGFR)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)	Enzyme-linked immunosorbent assay for Antigen Detection.
HEA757Hu	表皮生長因子受體(EGFR)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,高敏型)	Enzyme-linked immunosorbent assay for Antigen Detection.
AEA757Hu	抗表皮生長因子受體抗體(Anti-EGFR)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)	Enzyme-linked immunosorbent assay for Antibody Detection.
LMA757Hu	表皮生長因子受體(EGFR)等多因子檢測試劑盒(流式熒光發(fā)光法)	FLIA Kit for Antigen Detection.

參考文獻(xiàn)

雜志	參考文獻(xiàn)
Thoracic Cancer	Nimotuzumab combined with gemcitabine and cisplatin as second-line chemotherapy for advanced non-small-cell lung cancer [Wiley: source]
J Cent Nerv Syst Dis.?	Increased Epidermal Growth Factor Receptor (EGFR) Associated with Hepatocyte Growth Factor (HGF) and Symptom Severity in Children with Autism … [Pubmed:25249767]
Mol Cancer Ther	GC1118, an anti-EGFR antibody with a distinct binding epitope and superior inhibitory activity against high-affinity EGFR ligands [PubMed: 26586721]
Cell Death Dis.?	LINC01225 promotes occurrence and metastasis of hepatocellular carcinoma in an epidermal growth factor receptor-dependent pathway [Pubmed:26938303]
analytica chimica acta	Microfluidic immunosensor based on mesoporous silica platform and CMK-3/poly-acrylamide-co-methacrylate of dihydrolipoic acid modified gold electrode for cancer biomarker detection. [pubmed:28335979]
Talanta	EGFR detection in extracellular vesicles of breast cancer patients through immunosensor based on silica-chitosan nanoplatform [Doi: 10.1016/j.talanta.2018.10.016]
Bioorganic Chemistry	Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers [Pubmed: 30665034]
Journal of?enzyme?inhibition and medicinal chemistry	Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile [Pubmed: 30919701]
Bioorganic Chemistry	Design and synthesis of new benzoxazole/benzothiazole-phthalimide hybrids as antitumor-apoptotic agents []
Bioorganic Chemistry	Synthesis and anticancer activity of bis-benzo [d][1, 3] dioxol-5-yl thiourea derivatives with molecular docking study [Pubmed: 31288134]
Oxidative Medicine and Cellular Longevity	Evaluation of the Effect Derived from Silybin with Vitamin D and Vitamin E Administration on Clinical, Metabolic, Endothelial Dysfunction, Oxidative Stress Parameters?… [Pubmed: 31737175]
Neoplasia	Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine [Pubmed: 33212364]
	Association between Serum Epidermal Growth Factor Receptor and Cyclooxygenase-2 Levels in Patients with Non-small Cell Carcinoma of Lung []
	Synthesis, EGFR-TK inhibition and anticancer activity of new quinoxaline derivatives []
IMMUNOLOGIC RESEARCH	Humoral immune response to epidermal growth factor receptor in lung cancer [33495907]
European Journal of Medicinal Chemistry	Pyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structure¨Cactivity relationship and biological activity as potential antitumor and anticonvulsant agents [33545637]
Journal of Molecular Structure	Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors []
ACS Appl Mater Interfaces	Emitter–Quencher Pair of Single Atomic Co Sites and Monolayer Titanium Carbide MXenes for Luminol Chemiluminescent Reactions [34914377]
Bioorganic Chemistry	Discovery of new pyrimido [5, 4-c] quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies [Pubmed:35219045]

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