甲狀旁腺激素相關(guān)蛋白(PTHrP)單克隆抗體
Monoclonal Antibody to Parathyroid Hormone Related Protein (PTHrP)
PTHLH; HHM; PTHR; PLP; Osteostatin; Parathyroid Hormone Like Hormone
- 編號MAA819Ra21
- 物種Rattus norvegicus (Rat,大鼠) 相同的名稱,不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)C5
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標(biāo)記物無標(biāo)記物
- 免疫原 RPA819Ra01-甲狀旁腺激素相關(guān)蛋白(PTHrP)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性狀液體
- 濃度1mg/mL
- 且適物種Homo sapiens (Human,人)
- 應(yīng)用WB; IHC
如果抗體需用于流式細(xì)胞術(shù),請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 652 ¥ 1520 ¥ 2172 ¥ 5430 ¥ 21720
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特異性
該抗體是針對PTHrP的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別PTHrP。
用法
Western blotting: 0.01-3μg/mL;
Immunohistochemistry: 5-30μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲,損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
編號 | 適用物種:Rattus norvegicus (Rat,大鼠) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) |
RPA819Ra01 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
CPA819Ra21 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)卵白蛋白偶聯(lián)物 | Immunogen; SDS-PAGE; WB. |
CPA819Ra22 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)卵白蛋白偶聯(lián)物 | Immunogen; SDS-PAGE; WB. |
CPA819Ra31 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)鑰孔血藍(lán)蛋白偶聯(lián)物 | Immunogen; SDS-PAGE; WB. |
PAA819Ra01 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)多克隆抗體 | WB; IHC; ICC; IP. |
PAA819Ra08 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)多克隆抗體 | WB; IHC; ICC; IP. |
LAA819Ra71 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
LAA819Ra81 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)多克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. |
MAA819Ra24 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)單克隆抗體 | WB; IHC; ICC; IP. |
MAA819Ra21 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)單克隆抗體 | WB; IHC |
MAA819Ra22 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)單克隆抗體 | WB; IHC; ICC; IP. |
MAA819Ra23 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)單克隆抗體 | WB |
SEA819Ra | 甲狀旁腺激素相關(guān)蛋白(PTHrP)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
CEA819Ra | 甲狀旁腺激素相關(guān)蛋白(PTHrP)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMA819Ra | 甲狀旁腺激素相關(guān)蛋白(PTHrP)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
KSA819Ra11 | 甲狀旁腺激素相關(guān)蛋白(PTHrP)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻(xiàn)
雜志 | 參考文獻(xiàn) |
Clinical and Experimental Metastasis | Characterization of a new renal cell carcinoma bone metastasis mouse model [PubMed: 20443133] |
Stem Cells and Development | Temporal activation of β-catenin signaling in the chondrogenic process of mesenchymal stem cells affects the phenotype of the cartilage generated. [PubMed: 22133004] |
International journal of biological sciences | PTHrP Expression in Human MDA-MB-231 Breast Cancer Cells Is Critical for Tumor Growth and Survival and Osteoblast Inhibition [PubMed: PMC3753447] |
Investigational New Drugs | Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts [Pubmed: 23673814] |
Toxicology and Applied Pharmacology | Betulinic acid, a bioactive pentacyclic triterpenoid, inhibits skeletal-related events induced by breast cancer bone metastases and treatment [Pubmed:24463094] |
Arch Gynecol Obstet. | Calcitonin gene-and parathyroid hormone-related peptides in normotensive and preeclamptic pregnancies: a nested case–control study [Pubmed:24943060] |
PLoS One | 15-Deoxy-Δ12, 14-Prostaglandin J2 Inhibits Osteolytic Breast Cancer Bone Metastasis and Estrogen Deficiency-Induced Bone Loss [PubMed: 25859665] |
Endocrinology | A role for the calcitonin receptor to limit bone loss during lactation in female mice by inhibiting osteocytic osteolysis [PubMed: 26135836] |
Tumour Biol | Osteopontin expression in co-cultures of human squamous cell carcinoma-derived cells and osteoblastic cells and its effects on the neoplastic cell phenotype and osteoclastic activation. [Pubmed:27312487] |
35 | Hedgehog signaling in bone regulates whole-body energy metabolism through a bone–adipose endocrine relay mediated by PTHrP and adiponectin [pubmed:27740628] |
Bone | Lactation induces increases in the RANK/RANKL/OPG system in maxillary bone [Pubmed:29382610] |
International Journal of Molecular Sciences | A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice [Pubmed: 31600911] |
Journal of Orthopaedic Surgery and Research | Identification of a potential gene target for osteoarthritis based on bioinformatics analyses [Pubmed: 32571421] |
International Immunopharmacology | Parathyroid hormone related protein (PTHrP)-mediated hypercalcemia in malignancy associated with anti-PD-1 immune checkpoint inhibitor treatment and related?… [] |
Паратиреоидный гормон-родственный протеин как предиктор развития мочекаменной болезни [] | |
Cell Death Dis | Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer ?- [33510128] |
Sci Rep | Effects of whole-body vibration training in a cachectic C26 mouse model [34732809] |
Acta Physiologica | The acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals [Pubmed:35334154] |
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