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甲狀旁腺激素相關(guān)蛋白(PTHrP)重組蛋白

Recombinant Parathyroid Hormone Related Protein (PTHrP)

PTHLH; HHM; PTHR; PLP; Osteostatin; Parathyroid Hormone Like Hormone

編號(hào)RPA819Ra01
物種Rattus norvegicus (Rat，大鼠) 相同的名稱，不同的物種。
- 所有
- 人
- 小鼠
- 大鼠
- 豚鼠
- 家兔
- 獼猴
- 山羊
- 綿羊
- 馬
- 牛
- 豬
- 雞
- 狗
- 其他物種
- 多物種
- 泛物種
來源原核表達(dá)
宿主E.coli
內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
亞細(xì)胞定位細(xì)胞核, 分泌, 細(xì)胞質(zhì)
預(yù)測(cè)分子量22.7kDa
實(shí)際分子量27/33kDa(差異分析請(qǐng)參閱說明書)
片段與標(biāo)簽Ala37~His177 with N-terminal His Tag
緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
性狀凍干粉
純度> 95%
等電點(diǎn)9.5
應(yīng)用 Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見活性蛋白。
下載英文說明書中文說明書
規(guī)格 10μg50μg 200μg 1mg 5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)

Figure. Gene Sequencing (Extract)

Figure. SDS-PAGE

通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

序列

用法

Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

儲(chǔ)存

避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。

贈(zèng)品

聚丙烯酰胺凝膠電泳(PAGE)實(shí)驗(yàn)服務(wù)

增值服務(wù)

去內(nèi)毒素試劑盒
 BCA蛋白定量檢測(cè)試劑盒
 蛋白標(biāo)記定制服務(wù)
蛋白分子量MARKER
重組蛋白定制服務(wù)
單克隆抗體定制服務(wù)
多克隆抗體定制服務(wù)
蛋白活性測(cè)定實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
緩沖液
 內(nèi)毒素去除試劑盒Ⅱ
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
棘突蛋白受體結(jié)合結(jié)構(gòu)域
 蛋白G
蛋白 A

相關(guān)產(chǎn)品

編號(hào)	適用物種：Rattus norvegicus (Rat，大鼠)	應(yīng)用(僅供研究使用，不用于臨床診斷！)
RPA819Ra01	甲狀旁腺激素相關(guān)蛋白(PTHrP)重組蛋白	Positive Control; Immunogen; SDS-PAGE; WB.
CPA819Ra21	甲狀旁腺激素相關(guān)蛋白(PTHrP)卵白蛋白偶聯(lián)物	Immunogen; SDS-PAGE; WB.
CPA819Ra22	甲狀旁腺激素相關(guān)蛋白(PTHrP)卵白蛋白偶聯(lián)物	Immunogen; SDS-PAGE; WB.
CPA819Ra31	甲狀旁腺激素相關(guān)蛋白(PTHrP)鑰孔血藍(lán)蛋白偶聯(lián)物	Immunogen; SDS-PAGE; WB.
PAA819Ra01	甲狀旁腺激素相關(guān)蛋白(PTHrP)多克隆抗體	WB; IHC; ICC; IP.
PAA819Ra08	甲狀旁腺激素相關(guān)蛋白(PTHrP)多克隆抗體	WB; IHC; ICC; IP.
LAA819Ra71	甲狀旁腺激素相關(guān)蛋白(PTHrP)多克隆抗體(生物素標(biāo)記)	WB; IHC; ICC.
LAA819Ra81	甲狀旁腺激素相關(guān)蛋白(PTHrP)多克隆抗體(異硫氰酸熒光素標(biāo)記)	WB; IHC; ICC; IF.
MAA819Ra24	甲狀旁腺激素相關(guān)蛋白(PTHrP)單克隆抗體	WB; IHC; ICC; IP.
MAA819Ra21	甲狀旁腺激素相關(guān)蛋白(PTHrP)單克隆抗體	WB; IHC
MAA819Ra22	甲狀旁腺激素相關(guān)蛋白(PTHrP)單克隆抗體	WB; IHC; ICC; IP.
MAA819Ra23	甲狀旁腺激素相關(guān)蛋白(PTHrP)單克隆抗體	WB
SEA819Ra	甲狀旁腺激素相關(guān)蛋白(PTHrP)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)	Enzyme-linked immunosorbent assay for Antigen Detection.
CEA819Ra	甲狀旁腺激素相關(guān)蛋白(PTHrP)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMA819Ra	甲狀旁腺激素相關(guān)蛋白(PTHrP)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法)	FLIA Kit for Antigen Detection.
KSA819Ra11	甲狀旁腺激素相關(guān)蛋白(PTHrP)檢測(cè)試劑盒DIY材料(酶聯(lián)免疫吸附試驗(yàn)法)	Main materials for "Do It (ELISA Kit) Yourself".

參考文獻(xiàn)

雜志	參考文獻(xiàn)
Clinical and Experimental Metastasis	Characterization of a new renal cell carcinoma bone metastasis mouse model [PubMed: 20443133]
Stem Cells and Development	Temporal activation of β-catenin signaling in the chondrogenic process of mesenchymal stem cells affects the phenotype of the cartilage generated. [PubMed: 22133004]
International journal of biological sciences	PTHrP Expression in Human MDA-MB-231 Breast Cancer Cells Is Critical for Tumor Growth and Survival and Osteoblast Inhibition [PubMed: PMC3753447]
Investigational New Drugs	Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts [Pubmed: 23673814]
Toxicology and Applied Pharmacology	Betulinic acid, a bioactive pentacyclic triterpenoid, inhibits skeletal-related events induced by breast cancer bone metastases and treatment [Pubmed:24463094]
Arch Gynecol Obstet.	Calcitonin gene-and parathyroid hormone-related peptides in normotensive and preeclamptic pregnancies: a nested case–control study [Pubmed:24943060]
PLoS One	15-Deoxy-Δ12, 14-Prostaglandin J2 Inhibits Osteolytic Breast Cancer Bone Metastasis and Estrogen Deficiency-Induced Bone Loss [PubMed: 25859665]
Endocrinology	A role for the calcitonin receptor to limit bone loss during lactation in female mice by inhibiting osteocytic osteolysis [PubMed: 26135836]
Tumour Biol	Osteopontin expression in co-cultures of human squamous cell carcinoma-derived cells and osteoblastic cells and its effects on the neoplastic cell phenotype and osteoclastic activation. [Pubmed:27312487]
35	Hedgehog signaling in bone regulates whole-body energy metabolism through a bone–adipose endocrine relay mediated by PTHrP and adiponectin [pubmed:27740628]
Bone	Lactation induces increases in the RANK/RANKL/OPG system in maxillary bone [Pubmed:29382610]
International Journal of Molecular Sciences	A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice [Pubmed: 31600911]
Journal of Orthopaedic Surgery and Research	Identification of a potential gene target for osteoarthritis based on bioinformatics analyses [Pubmed: 32571421]
International Immunopharmacology	Parathyroid hormone related protein (PTHrP)-mediated hypercalcemia in malignancy associated with anti-PD-1 immune checkpoint inhibitor treatment and related?… []
	Паратиреоидный гормон-родственный протеин как предиктор развития мочекаменной болезни []
Cell Death Dis	Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer ?- [33510128]
Sci Rep	Effects of whole-body vibration training in a cachectic C26 mouse model [34732809]
Acta Physiologica	The acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals [Pubmed:35334154]

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