胰島素降解酶(IDE)單克隆抗體
Monoclonal Antibody to Insulin Degrading Enzyme (IDE)
Insulysin; Insulin Protease; Abeta-degrading protease; Insulinase
- 編號MAB897Hu22
- 物種Homo sapiens (Human,人) 相同的名稱,不同的物種。
- 來源單抗制備
- 宿主小鼠
- 效價(克隆號)C2
- Ig亞型 IgG1 Kappa
- 純化方式蛋白A + 蛋白G親和純化
- 標記物無標記物
- 免疫原 RPB897Hu01-胰島素降解酶(IDE)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液(pH7.4,containing 0.05% Proclin-300,50% glycerol)
- 性狀液體
- 濃度0.8mg/mL
- 且適物種-
- 應(yīng)用WB; IHC; ICC; IP.
如果抗體需用于流式細胞術(shù),請參見流式抗體。 - 下載 英文說明書 中文說明書
- 規(guī)格 20μl100μl 200μl 1ml 10ml
- 價格 ¥ 634 ¥ 1478 ¥ 2112 ¥ 5280 ¥ 21120
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特異性
該抗體是針對IDE的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別IDE。
用法
Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunofluorescence:5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當?shù)臈l件下存儲,損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
編號 | 適用物種:Homo sapiens (Human,人) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) |
RPB897Hu01 | 胰島素降解酶(IDE)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
APB897Hu01 | 胰島素降解酶(IDE)活性蛋白 | Cell?culture;?Activity?Assays. |
PAB897Hu01 | 胰島素降解酶(IDE)多克隆抗體 | WB; IHC |
MAB897Hu21 | 胰島素降解酶(IDE)單克隆抗體 | WB; IHC; ICC; IP. |
MAB897Hu22 | 胰島素降解酶(IDE)單克隆抗體 | WB; IHC; ICC; IP. |
SEB897Hu | 胰島素降解酶(IDE)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMB897Hu | 胰島素降解酶(IDE)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
KSB897Hu01 | 胰島素降解酶(IDE)檢測試劑盒DIY材料(酶聯(lián)免疫吸附試驗法) | 自己動手制作ELISA試劑盒的主要材料 |
參考文獻
雜志 | 參考文獻 |
J Neurochem | Reduction [PubMed: 26442993] |
African Journal of Pharmacy and Pharmacology | Peptide hydroxamate derivatives as regulators for insulin receptor signaling and its degradation by zinc metalloprotease in diabetic rats [article-full-text-pdf] |
Biomedicine & Pharmacotherapy | Vitamin?D3?intake?as?regulator?of?insulin?degrading?enzyme?and?insulin?receptor?phosphorylationin?diabetic?rats. [pubmed:27930980] |
Biological Trace Element Research | Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats [10.1007/s12011-017-1167-z] |
Neuroscience | The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A [Pubmed:29406271] |
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